Amipramizide

• Diuretics
• ATC:C03DB01

• AMR
• Amilorida [INN-Spanish]
• Amiloride HCL
• Amiloride hydrochloride
• Amiloridum [INN-Latin]
• Amipramidin
• Amipramizid
• Amipramizide
• Amiprazidine
• Guanamprazin
• Guanamprazine
• Midamor
• Amiloride hydrochloride hydrate

• Blu Kote Dr Naylors (Acriflavine + Gentian Violet + Glycerine + Isopropyl Alcohol + Sodium Propionate + Urea)
• Blue Lotion (Gentian Violet + Methylene Blue + Tannic Acid)
• Co-Op Pinkeye Spray (Gentian Violet + Neomycin (Neomycin Sulfate))
• Cristisol (Acriflavine + Gentian Violet + Isopropyl Alcohol)
• Pink Eye Guard (Allantoin + Boric Acid + Gentian Violet)
• Pink Eye Spray (Furfural + Gentian Violet + Isopropyl Alcohol + Methylene Blue + Phenylmercuric Nitrate (Basic) + Tetrahydrofurfuryl Alcohol + Urea)
• Pinkeye Spray (Gentian Violet + Neomycin (Neomycin Sulfate))
• Triple Dye (Brilliant Green + Gentian Violet + Proflavine Hemisulfate)
• Wound & Pinkeye Spray (Gentian Violet + Neomycin (Neomycin Sulfate))
• Wound Kote Gentian Violet Spray Wound Dre (Acriflavine + Furfural + Methyl Violet + Sodium Propionate + Urea)

C₆H₈ClN₇O

http://www.rxlist.com/cgi/generic2/amilor.htm

Amipramizide FDA

Amipramizide MSDS

Cragoe, Belg, pat. 639,386 (1964 to Merck & Co.), C.A. 62, 14698f (1965)

229.627 g/mol

240 ^oC

Slightly soluble

Solid

-1.245

Tablets (oral, 5mg)

For use as adjunctive treatment with thiazide diuretics or other kaliuretic-diuretic agents in congestive heart failure or hypertension.

Amiloride, an antikaliuretic-diuretic agent, is a pyrazine-carbonyl-guanidine that is unrelated chemically to other known antikaliuretic or diuretic agents. It is an antihypertensive, potassium-sparing diuretic that was first approved for use in 1967 and helps to treat hypertension and congestive heart failure. The drug is often used in conjunction with thiazide or loop diuretics. Due to its potassium-sparing capacities, hyperkalemia (high blood potassium levels) are occasionally observed in patients taking amiloride. The risk is high in concurrent use of ACE inhibitors or spironolactone. Patients are also advised not to use potassium-containing salt replacements.

Readily absorbed following oral administration.

No data are available in regard to overdosage in humans. The oral LD₅₀ of amiloride hydrochloride (calculated as the base) is 56 mg/kg in mice and 36 to 85 mg/kg in rats, depending on the strain. The most likely signs and symptoms to be expected with overdosage are dehydration and electrolyte imbalance.

No information avaliable

Humans and other mammals