Amiloride hydrochloride en es it fr

Amiloride hydrochloride Brand names, Amiloride hydrochloride Analogs

Amiloride hydrochloride Brand Names Mixture

  • Blu Kote Dr Naylors (Acriflavine + Gentian Violet + Glycerine + Isopropyl Alcohol + Sodium Propionate + Urea)
  • Blue Lotion (Gentian Violet + Methylene Blue + Tannic Acid)
  • Co-Op Pinkeye Spray (Gentian Violet + Neomycin (Neomycin Sulfate))
  • Cristisol (Acriflavine + Gentian Violet + Isopropyl Alcohol)
  • Pink Eye Guard (Allantoin + Boric Acid + Gentian Violet)
  • Pink Eye Spray (Furfural + Gentian Violet + Isopropyl Alcohol + Methylene Blue + Phenylmercuric Nitrate (Basic) + Tetrahydrofurfuryl Alcohol + Urea)
  • Pinkeye Spray (Gentian Violet + Neomycin (Neomycin Sulfate))
  • Triple Dye (Brilliant Green + Gentian Violet + Proflavine Hemisulfate)
  • Wound & Pinkeye Spray (Gentian Violet + Neomycin (Neomycin Sulfate))
  • Wound Kote Gentian Violet Spray Wound Dre (Acriflavine + Furfural + Methyl Violet + Sodium Propionate + Urea)

Amiloride hydrochloride Chemical_Formula


Amiloride hydrochloride RX_link

Amiloride hydrochloride fda sheet

Amiloride_hydrochloride FDA

Amiloride hydrochloride msds (material safety sheet)

Amiloride_hydrochloride MSDS

Amiloride hydrochloride Synthesis Reference

Cragoe, Belg, pat. 639,386 (1964 to Merck & Co.), C.A. 62, 14698f (1965)

Amiloride hydrochloride Molecular Weight

229.627 g/mol

Amiloride hydrochloride Melting Point

240 oC

Amiloride hydrochloride H2O Solubility

Slightly soluble

Amiloride hydrochloride State


Amiloride hydrochloride LogP


Amiloride hydrochloride Dosage Forms

Tablets (oral, 5mg)

Amiloride hydrochloride Indication

For use as adjunctive treatment with thiazide diuretics or other kaliuretic-diuretic agents in congestive heart failure or hypertension.

Amiloride hydrochloride Pharmacology

Amiloride, an antikaliuretic-diuretic agent, is a pyrazine-carbonyl-guanidine that is unrelated chemically to other known antikaliuretic or diuretic agents. It is an antihypertensive, potassium-sparing diuretic that was first approved for use in 1967 and helps to treat hypertension and congestive heart failure. The drug is often used in conjunction with thiazide or loop diuretics. Due to its potassium-sparing capacities, hyperkalemia (high blood potassium levels) are occasionally observed in patients taking amiloride. The risk is high in concurrent use of ACE inhibitors or spironolactone. Patients are also advised not to use potassium-containing salt replacements.

Amiloride hydrochloride Absorption

Readily absorbed following oral administration.

Amiloride hydrochloride side effects and Toxicity

No data are available in regard to overdosage in humans. The oral LD50 of amiloride hydrochloride (calculated as the base) is 56 mg/kg in mice and 36 to 85 mg/kg in rats, depending on the strain. The most likely signs and symptoms to be expected with overdosage are dehydration and electrolyte imbalance.

Amiloride hydrochloride Patient Information

No information avaliable

Amiloride hydrochloride Organisms Affected

Humans and other mammals