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Amiprazidine Brand names, Amiprazidine Analogs

Amiprazidine Brand Names Mixture

  • Blu Kote Dr Naylors (Acriflavine + Gentian Violet + Glycerine + Isopropyl Alcohol + Sodium Propionate + Urea)
  • Blue Lotion (Gentian Violet + Methylene Blue + Tannic Acid)
  • Co-Op Pinkeye Spray (Gentian Violet + Neomycin (Neomycin Sulfate))
  • Cristisol (Acriflavine + Gentian Violet + Isopropyl Alcohol)
  • Pink Eye Guard (Allantoin + Boric Acid + Gentian Violet)
  • Pink Eye Spray (Furfural + Gentian Violet + Isopropyl Alcohol + Methylene Blue + Phenylmercuric Nitrate (Basic) + Tetrahydrofurfuryl Alcohol + Urea)
  • Pinkeye Spray (Gentian Violet + Neomycin (Neomycin Sulfate))
  • Triple Dye (Brilliant Green + Gentian Violet + Proflavine Hemisulfate)
  • Wound & Pinkeye Spray (Gentian Violet + Neomycin (Neomycin Sulfate))
  • Wound Kote Gentian Violet Spray Wound Dre (Acriflavine + Furfural + Methyl Violet + Sodium Propionate + Urea)

Amiprazidine Chemical_Formula

C6H8ClN7O

Amiprazidine RX_link

http://www.rxlist.com/cgi/generic2/amilor.htm

Amiprazidine fda sheet

Amiprazidine FDA

Amiprazidine msds (material safety sheet)

Amiprazidine MSDS

Amiprazidine Synthesis Reference

Cragoe, Belg, pat. 639,386 (1964 to Merck & Co.), C.A. 62, 14698f (1965)

Amiprazidine Molecular Weight

229.627 g/mol

Amiprazidine Melting Point

240 oC

Amiprazidine H2O Solubility

Slightly soluble

Amiprazidine State

Solid

Amiprazidine LogP

-1.245

Amiprazidine Dosage Forms

Tablets (oral, 5mg)

Amiprazidine Indication

For use as adjunctive treatment with thiazide diuretics or other kaliuretic-diuretic agents in congestive heart failure or hypertension.

Amiprazidine Pharmacology

Amiloride, an antikaliuretic-diuretic agent, is a pyrazine-carbonyl-guanidine that is unrelated chemically to other known antikaliuretic or diuretic agents. It is an antihypertensive, potassium-sparing diuretic that was first approved for use in 1967 and helps to treat hypertension and congestive heart failure. The drug is often used in conjunction with thiazide or loop diuretics. Due to its potassium-sparing capacities, hyperkalemia (high blood potassium levels) are occasionally observed in patients taking amiloride. The risk is high in concurrent use of ACE inhibitors or spironolactone. Patients are also advised not to use potassium-containing salt replacements.

Amiprazidine Absorption

Readily absorbed following oral administration.

Amiprazidine side effects and Toxicity

No data are available in regard to overdosage in humans. The oral LD50 of amiloride hydrochloride (calculated as the base) is 56 mg/kg in mice and 36 to 85 mg/kg in rats, depending on the strain. The most likely signs and symptoms to be expected with overdosage are dehydration and electrolyte imbalance.

Amiprazidine Patient Information

No information avaliable

Amiprazidine Organisms Affected

Humans and other mammals