PharmacyCodes



Amilorida [INN-Spanish] en es it fr

Amilorida [INN-Spanish] Brand names, Amilorida [INN-Spanish] Analogs

Amilorida [INN-Spanish] Brand Names Mixture

  • Blu Kote Dr Naylors (Acriflavine + Gentian Violet + Glycerine + Isopropyl Alcohol + Sodium Propionate + Urea)
  • Blue Lotion (Gentian Violet + Methylene Blue + Tannic Acid)
  • Co-Op Pinkeye Spray (Gentian Violet + Neomycin (Neomycin Sulfate))
  • Cristisol (Acriflavine + Gentian Violet + Isopropyl Alcohol)
  • Pink Eye Guard (Allantoin + Boric Acid + Gentian Violet)
  • Pink Eye Spray (Furfural + Gentian Violet + Isopropyl Alcohol + Methylene Blue + Phenylmercuric Nitrate (Basic) + Tetrahydrofurfuryl Alcohol + Urea)
  • Pinkeye Spray (Gentian Violet + Neomycin (Neomycin Sulfate))
  • Triple Dye (Brilliant Green + Gentian Violet + Proflavine Hemisulfate)
  • Wound & Pinkeye Spray (Gentian Violet + Neomycin (Neomycin Sulfate))
  • Wound Kote Gentian Violet Spray Wound Dre (Acriflavine + Furfural + Methyl Violet + Sodium Propionate + Urea)

Amilorida [INN-Spanish] Chemical_Formula

C6H8ClN7O

Amilorida [INN-Spanish] RX_link

http://www.rxlist.com/cgi/generic2/amilor.htm

Amilorida [INN-Spanish] fda sheet

Amilorida_[INN-Spanish] FDA

Amilorida [INN-Spanish] msds (material safety sheet)

Amilorida_[INN-Spanish] MSDS

Amilorida [INN-Spanish] Synthesis Reference

Cragoe, Belg, pat. 639,386 (1964 to Merck & Co.), C.A. 62, 14698f (1965)

Amilorida [INN-Spanish] Molecular Weight

229.627 g/mol

Amilorida [INN-Spanish] Melting Point

240 oC

Amilorida [INN-Spanish] H2O Solubility

Slightly soluble

Amilorida [INN-Spanish] State

Solid

Amilorida [INN-Spanish] LogP

-1.245

Amilorida [INN-Spanish] Dosage Forms

Tablets (oral, 5mg)

Amilorida [INN-Spanish] Indication

For use as adjunctive treatment with thiazide diuretics or other kaliuretic-diuretic agents in congestive heart failure or hypertension.

Amilorida [INN-Spanish] Pharmacology

Amiloride, an antikaliuretic-diuretic agent, is a pyrazine-carbonyl-guanidine that is unrelated chemically to other known antikaliuretic or diuretic agents. It is an antihypertensive, potassium-sparing diuretic that was first approved for use in 1967 and helps to treat hypertension and congestive heart failure. The drug is often used in conjunction with thiazide or loop diuretics. Due to its potassium-sparing capacities, hyperkalemia (high blood potassium levels) are occasionally observed in patients taking amiloride. The risk is high in concurrent use of ACE inhibitors or spironolactone. Patients are also advised not to use potassium-containing salt replacements.

Amilorida [INN-Spanish] Absorption

Readily absorbed following oral administration.

Amilorida [INN-Spanish] side effects and Toxicity

No data are available in regard to overdosage in humans. The oral LD50 of amiloride hydrochloride (calculated as the base) is 56 mg/kg in mice and 36 to 85 mg/kg in rats, depending on the strain. The most likely signs and symptoms to be expected with overdosage are dehydration and electrolyte imbalance.

Amilorida [INN-Spanish] Patient Information

No information avaliable

Amilorida [INN-Spanish] Organisms Affected

Humans and other mammals