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Guanamprazine Brand names, Guanamprazine Analogs

Guanamprazine Brand Names Mixture

  • Blu Kote Dr Naylors (Acriflavine + Gentian Violet + Glycerine + Isopropyl Alcohol + Sodium Propionate + Urea)
  • Blue Lotion (Gentian Violet + Methylene Blue + Tannic Acid)
  • Co-Op Pinkeye Spray (Gentian Violet + Neomycin (Neomycin Sulfate))
  • Cristisol (Acriflavine + Gentian Violet + Isopropyl Alcohol)
  • Pink Eye Guard (Allantoin + Boric Acid + Gentian Violet)
  • Pink Eye Spray (Furfural + Gentian Violet + Isopropyl Alcohol + Methylene Blue + Phenylmercuric Nitrate (Basic) + Tetrahydrofurfuryl Alcohol + Urea)
  • Pinkeye Spray (Gentian Violet + Neomycin (Neomycin Sulfate))
  • Triple Dye (Brilliant Green + Gentian Violet + Proflavine Hemisulfate)
  • Wound & Pinkeye Spray (Gentian Violet + Neomycin (Neomycin Sulfate))
  • Wound Kote Gentian Violet Spray Wound Dre (Acriflavine + Furfural + Methyl Violet + Sodium Propionate + Urea)

Guanamprazine Chemical_Formula

C6H8ClN7O

Guanamprazine RX_link

http://www.rxlist.com/cgi/generic2/amilor.htm

Guanamprazine fda sheet

Guanamprazine FDA

Guanamprazine msds (material safety sheet)

Guanamprazine MSDS

Guanamprazine Synthesis Reference

Cragoe, Belg, pat. 639,386 (1964 to Merck & Co.), C.A. 62, 14698f (1965)

Guanamprazine Molecular Weight

229.627 g/mol

Guanamprazine Melting Point

240 oC

Guanamprazine H2O Solubility

Slightly soluble

Guanamprazine State

Solid

Guanamprazine LogP

-1.245

Guanamprazine Dosage Forms

Tablets (oral, 5mg)

Guanamprazine Indication

For use as adjunctive treatment with thiazide diuretics or other kaliuretic-diuretic agents in congestive heart failure or hypertension.

Guanamprazine Pharmacology

Amiloride, an antikaliuretic-diuretic agent, is a pyrazine-carbonyl-guanidine that is unrelated chemically to other known antikaliuretic or diuretic agents. It is an antihypertensive, potassium-sparing diuretic that was first approved for use in 1967 and helps to treat hypertension and congestive heart failure. The drug is often used in conjunction with thiazide or loop diuretics. Due to its potassium-sparing capacities, hyperkalemia (high blood potassium levels) are occasionally observed in patients taking amiloride. The risk is high in concurrent use of ACE inhibitors or spironolactone. Patients are also advised not to use potassium-containing salt replacements.

Guanamprazine Absorption

Readily absorbed following oral administration.

Guanamprazine side effects and Toxicity

No data are available in regard to overdosage in humans. The oral LD50 of amiloride hydrochloride (calculated as the base) is 56 mg/kg in mice and 36 to 85 mg/kg in rats, depending on the strain. The most likely signs and symptoms to be expected with overdosage are dehydration and electrolyte imbalance.

Guanamprazine Patient Information

No information avaliable

Guanamprazine Organisms Affected

Humans and other mammals