Alglucerase
Alglucerase Brand names, Alglucerase Analogs
Alglucerase Brand Names Mixture
- No information avaliable
Alglucerase Chemical_Formula
C2532H3854N672O711S16
Alglucerase RX_link
http://www.rxlist.com/cgi/generic3/ceredase.htm
Alglucerase fda sheet
Alglucerase msds (material safety sheet)
Alglucerase Synthesis Reference
No information avaliable
Alglucerase Molecular Weight
55597.4
Alglucerase Melting Point
No information avaliable
Alglucerase H2O Solubility
No information avaliable
Alglucerase State
Liquid
Alglucerase LogP
-0.168
Alglucerase Dosage Forms
Solution (IV Infusion)
Alglucerase Indication
For the treatment of Gaucher's disease (deficiency in glucocerebrosidase)
Alglucerase Pharmacology
Gaucher disease is characterized by a functional deficiency in Beta-glucocerebrosidase enzymatic activity and the resultant accumulation of lipid glucocerebroside in tissue macrophages which become engorged and are termed Gaucher cells. Gaucher cells are typically found in liver, spleen and bone marrow. This can lead to an enlarged spleen and liver (hepatosplenomegaly). Secondary hematologic sequelae include severe anemia and thrombocytopenia. Injections of alglucerase into Gaucher disease patients leads to elevated serum levels of the enzyme and reduction in the accumulation of glucocerebroside
Alglucerase Absorption
No information avaliable
Alglucerase side effects and Toxicity
No information avaliable
Alglucerase Patient Information
No information avaliable
Alglucerase Organisms Affected
Humans and other mammals
