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D-glucosyl-N-acylsphingosine glucohydrolase en es it fr

D-glucosyl-N-acylsphingosine glucohydrolase Brand names, D-glucosyl-N-acylsphingosine glucohydrolase Analogs

D-glucosyl-N-acylsphingosine glucohydrolase Brand Names Mixture

  • No information avaliable

D-glucosyl-N-acylsphingosine glucohydrolase Chemical_Formula

C2532H3854N672O711S16

D-glucosyl-N-acylsphingosine glucohydrolase RX_link

http://www.rxlist.com/cgi/generic2/imiglucerase.htm

D-glucosyl-N-acylsphingosine glucohydrolase fda sheet

D-glucosyl-N-acylsphingosine glucohydrolase msds (material safety sheet)

D-glucosyl-N-acylsphingosine glucohydrolase Synthesis Reference

No information avaliable

D-glucosyl-N-acylsphingosine glucohydrolase Molecular Weight

55597.4

D-glucosyl-N-acylsphingosine glucohydrolase Melting Point

No information avaliable

D-glucosyl-N-acylsphingosine glucohydrolase H2O Solubility

No information avaliable

D-glucosyl-N-acylsphingosine glucohydrolase State

Liquid

D-glucosyl-N-acylsphingosine glucohydrolase LogP

-0.168

D-glucosyl-N-acylsphingosine glucohydrolase Dosage Forms

Powder for solution; Solution (IV injection)

D-glucosyl-N-acylsphingosine glucohydrolase Indication

For the treatment of Gaucher's disease (deficiency in glucocerebrosidase)

D-glucosyl-N-acylsphingosine glucohydrolase Pharmacology

Gaucher disease is characterized by a functional deficiency in Beta-glucocerebrosidase enzymatic activity and the resultant accumulation of lipid glucocerebroside in tissue macrophages which become engorged and are termed Gaucher cells. Gaucher cells are typically found in liver, spleen and bone marrow. This can lead to an enlarged spleen and liver (hepatosplenomegaly). Secondary hematologic sequelae include severe anemia and thrombocytopenia. Injections of imiglucerase into Gaucher disease patients leads to elevated serum levels of the enzyme and reduction in the accumulation of glucocerebroside leading to reduced anemia and thrombocytopenia, reduced spleen and liver size, and decreased cachexia

D-glucosyl-N-acylsphingosine glucohydrolase Absorption

No information avaliable

D-glucosyl-N-acylsphingosine glucohydrolase side effects and Toxicity

No information avaliable

D-glucosyl-N-acylsphingosine glucohydrolase Patient Information

No information avaliable

D-glucosyl-N-acylsphingosine glucohydrolase Organisms Affected

Humans and other mammals