Imiglucerase
Imiglucerase Brand names, Imiglucerase Analogs
Imiglucerase Brand Names Mixture
- No information avaliable
Imiglucerase Chemical_Formula
C2532H3854N672O711S16
Imiglucerase RX_link
http://www.rxlist.com/cgi/generic2/imiglucerase.htm
Imiglucerase fda sheet
Imiglucerase msds (material safety sheet)
Imiglucerase Synthesis Reference
No information avaliable
Imiglucerase Molecular Weight
55597.4
Imiglucerase Melting Point
No information avaliable
Imiglucerase H2O Solubility
No information avaliable
Imiglucerase State
Liquid
Imiglucerase LogP
-0.168
Imiglucerase Dosage Forms
Powder for solution; Solution (IV injection)
Imiglucerase Indication
For the treatment of Gaucher's disease (deficiency in glucocerebrosidase)
Imiglucerase Pharmacology
Gaucher disease is characterized by a functional deficiency in Beta-glucocerebrosidase enzymatic activity and the resultant accumulation of lipid glucocerebroside in tissue macrophages which become engorged and are termed Gaucher cells. Gaucher cells are typically found in liver, spleen and bone marrow. This can lead to an enlarged spleen and liver (hepatosplenomegaly). Secondary hematologic sequelae include severe anemia and thrombocytopenia. Injections of imiglucerase into Gaucher disease patients leads to elevated serum levels of the enzyme and reduction in the accumulation of glucocerebroside leading to reduced anemia and thrombocytopenia, reduced spleen and liver size, and decreased cachexia
Imiglucerase Absorption
No information avaliable
Imiglucerase side effects and Toxicity
No information avaliable
Imiglucerase Patient Information
No information avaliable
Imiglucerase Organisms Affected
Humans and other mammals
