Imiglucerase en es it fr

Imiglucerase Brand names, Imiglucerase Analogs

Imiglucerase Brand Names Mixture

  • No information avaliable

Imiglucerase Chemical_Formula

C2532H3854N672O711S16

Imiglucerase RX_link

http://www.rxlist.com/cgi/generic2/imiglucerase.htm

Imiglucerase fda sheet

Imiglucerase msds (material safety sheet)

Imiglucerase Synthesis Reference

No information avaliable

Imiglucerase Molecular Weight

55597.4

Imiglucerase Melting Point

No information avaliable

Imiglucerase H2O Solubility

No information avaliable

Imiglucerase State

Liquid

Imiglucerase LogP

-0.168

Imiglucerase Dosage Forms

Powder for solution; Solution (IV injection)

Imiglucerase Indication

For the treatment of Gaucher's disease (deficiency in glucocerebrosidase)

Imiglucerase Pharmacology

Gaucher disease is characterized by a functional deficiency in Beta-glucocerebrosidase enzymatic activity and the resultant accumulation of lipid glucocerebroside in tissue macrophages which become engorged and are termed Gaucher cells. Gaucher cells are typically found in liver, spleen and bone marrow. This can lead to an enlarged spleen and liver (hepatosplenomegaly). Secondary hematologic sequelae include severe anemia and thrombocytopenia. Injections of imiglucerase into Gaucher disease patients leads to elevated serum levels of the enzyme and reduction in the accumulation of glucocerebroside leading to reduced anemia and thrombocytopenia, reduced spleen and liver size, and decreased cachexia

Imiglucerase Absorption

No information avaliable

Imiglucerase side effects and Toxicity

No information avaliable

Imiglucerase Patient Information

No information avaliable

Imiglucerase Organisms Affected

Humans and other mammals