Ceredase (Genzyme Corp)
Brand names,
Ceredase (Genzyme Corp)
Analogs
Ceredase (Genzyme Corp)
Brand Names Mixture
Ceredase (Genzyme Corp)
Chemical_Formula
C2532H3854N672O711S16
Ceredase (Genzyme Corp)
RX_link
http://www.rxlist.com/cgi/generic3/ceredase.htm
Ceredase (Genzyme Corp)
fda sheet
Ceredase (Genzyme Corp)
msds (material safety sheet)
Ceredase (Genzyme Corp)
Synthesis Reference
No information avaliable
Ceredase (Genzyme Corp)
Molecular Weight
55597.4
Ceredase (Genzyme Corp)
Melting Point
No information avaliable
Ceredase (Genzyme Corp)
H2O Solubility
No information avaliable
Ceredase (Genzyme Corp)
State
Liquid
Ceredase (Genzyme Corp)
LogP
-0.168
Ceredase (Genzyme Corp)
Dosage Forms
Solution (IV Infusion)
Ceredase (Genzyme Corp)
Indication
For the treatment of Gaucher's disease (deficiency in glucocerebrosidase)
Ceredase (Genzyme Corp)
Pharmacology
Gaucher disease is characterized by a functional deficiency in Beta-glucocerebrosidase enzymatic activity and the resultant accumulation of lipid glucocerebroside in tissue macrophages which become engorged and are termed Gaucher cells. Gaucher cells are typically found in liver, spleen and bone marrow. This can lead to an enlarged spleen and liver (hepatosplenomegaly). Secondary hematologic sequelae include severe anemia and thrombocytopenia. Injections of alglucerase into Gaucher disease patients leads to elevated serum levels of the enzyme and reduction in the accumulation of glucocerebroside
Ceredase (Genzyme Corp)
Absorption
No information avaliable
Ceredase (Genzyme Corp)
side effects and Toxicity
No information avaliable
Ceredase (Genzyme Corp)
Patient Information
No information avaliable
Ceredase (Genzyme Corp)
Organisms Affected
Humans and other mammals