Glucosylceramidase precursor en es it fr

Glucosylceramidase precursor Brand names, Glucosylceramidase precursor Analogs

Glucosylceramidase precursor Brand Names Mixture

  • No information avaliable

Glucosylceramidase precursor Chemical_Formula

C2532H3854N672O711S16

Glucosylceramidase precursor RX_link

http://www.rxlist.com/cgi/generic2/imiglucerase.htm

Glucosylceramidase precursor fda sheet

Glucosylceramidase precursor msds (material safety sheet)

Glucosylceramidase precursor Synthesis Reference

No information avaliable

Glucosylceramidase precursor Molecular Weight

55597.4

Glucosylceramidase precursor Melting Point

No information avaliable

Glucosylceramidase precursor H2O Solubility

No information avaliable

Glucosylceramidase precursor State

Liquid

Glucosylceramidase precursor LogP

-0.168

Glucosylceramidase precursor Dosage Forms

Powder for solution; Solution (IV injection)

Glucosylceramidase precursor Indication

For the treatment of Gaucher's disease (deficiency in glucocerebrosidase)

Glucosylceramidase precursor Pharmacology

Gaucher disease is characterized by a functional deficiency in Beta-glucocerebrosidase enzymatic activity and the resultant accumulation of lipid glucocerebroside in tissue macrophages which become engorged and are termed Gaucher cells. Gaucher cells are typically found in liver, spleen and bone marrow. This can lead to an enlarged spleen and liver (hepatosplenomegaly). Secondary hematologic sequelae include severe anemia and thrombocytopenia. Injections of imiglucerase into Gaucher disease patients leads to elevated serum levels of the enzyme and reduction in the accumulation of glucocerebroside leading to reduced anemia and thrombocytopenia, reduced spleen and liver size, and decreased cachexia

Glucosylceramidase precursor Absorption

No information avaliable

Glucosylceramidase precursor side effects and Toxicity

No information avaliable

Glucosylceramidase precursor Patient Information

No information avaliable

Glucosylceramidase precursor Organisms Affected

Humans and other mammals