Acid beta-glucosidase
Acid beta-glucosidase Brand names, Acid beta-glucosidase Analogs
Acid beta-glucosidase Brand Names Mixture
- No information avaliable
Acid beta-glucosidase Chemical_Formula
C2532H3854N672O711S16
Acid beta-glucosidase RX_link
http://www.rxlist.com/cgi/generic2/imiglucerase.htm
Acid beta-glucosidase fda sheet
Acid beta-glucosidase msds (material safety sheet)
Acid beta-glucosidase Synthesis Reference
No information avaliable
Acid beta-glucosidase Molecular Weight
55597.4
Acid beta-glucosidase Melting Point
No information avaliable
Acid beta-glucosidase H2O Solubility
No information avaliable
Acid beta-glucosidase State
Liquid
Acid beta-glucosidase LogP
-0.168
Acid beta-glucosidase Dosage Forms
Powder for solution; Solution (IV injection)
Acid beta-glucosidase Indication
For the treatment of Gaucher's disease (deficiency in glucocerebrosidase)
Acid beta-glucosidase Pharmacology
Gaucher disease is characterized by a functional deficiency in Beta-glucocerebrosidase enzymatic activity and the resultant accumulation of lipid glucocerebroside in tissue macrophages which become engorged and are termed Gaucher cells. Gaucher cells are typically found in liver, spleen and bone marrow. This can lead to an enlarged spleen and liver (hepatosplenomegaly). Secondary hematologic sequelae include severe anemia and thrombocytopenia. Injections of imiglucerase into Gaucher disease patients leads to elevated serum levels of the enzyme and reduction in the accumulation of glucocerebroside leading to reduced anemia and thrombocytopenia, reduced spleen and liver size, and decreased cachexia
Acid beta-glucosidase Absorption
No information avaliable
Acid beta-glucosidase side effects and Toxicity
No information avaliable
Acid beta-glucosidase Patient Information
No information avaliable
Acid beta-glucosidase Organisms Affected
Humans and other mammals
