Solage

Solage Brand names, Solage Analogs

Solage Brand Names Mixture

No information avaliable

Solage Chemical_Formula

C₂₀H₂₈O₂

Solage RX_link

http://www.rxlist.com/cgi/generic/tretinoin.htm

Solage fda sheet

Solage FDA

Solage msds (material safety sheet)

Solage MSDS

Solage Synthesis Reference

Matsui et al.; J.Vitaminol.; 4; 190, 192(1958)

Solage Molecular Weight

300.435 g/mol

Solage Melting Point

181 ^oC

Solage H₂O Solubility

<0.1 g/100 mL

Solage State

Solid

Solage LogP

5.067

Solage Dosage Forms

Capsule; Cream; Gel; Liquid

Solage Indication

For the the induction of remission in patients with acute promyelocytic leukemia (APL), French-American-British (FAB) classification M3 (including the M3 variant); For the topical treatment of acne vulgaris, flat warts and other skin conditions (psoriasis, ichthyosis congenita, icthyosis vulgaris, lamellar icthyosis, keratosis palmaris et plantaris, epidermolytic hyperkeratosis, senile comedones, senile keratosis, keratosis follicularis (Darier's disease), and basal cell carcinomas.); For palliative therapy to improve fine wrinkling, mottled hyperpigmentation, roughness associated with photodamage.

Solage Pharmacology

Tretinoin, also known as all-trans-retinoic acid (ATRA), is a naturally occurring derivative of vitamin A (retinol). Retinoids such as tretinoin are important regulators of cell reproduction, proliferation, and differentiation and are used to treat acne and photodamaged skin and to manage keratinization disorders such as ichthyosis and keratosis follicularis. Tretinoin also represents the class of anticancer drugs called differentiating agents and is used in the treatment of acute promyelocytic leukemia (APL).

Solage Absorption

1-31% (topical);

Solage side effects and Toxicity

No information avaliable

Solage Patient Information