Airol
Category
Airol Brand names, Airol Analogs
Airol Brand Names Mixture
No information avaliable
Airol Chemical_Formula
C20H28O2
Airol RX_link
http://www.rxlist.com/cgi/generic/tretinoin.htm
Airol fda sheet
Airol msds (material safety sheet)
Airol Synthesis Reference
Matsui et al.; J.Vitaminol.; 4; 190, 192(1958)
Airol Molecular Weight
300.435 g/mol
Airol Melting Point
181 oC
Airol H2O Solubility
<0.1 g/100 mL
Airol State
Solid
Airol LogP
5.067
Airol Dosage Forms
Capsule; Cream; Gel; Liquid
Airol Indication
For the the induction of remission in patients with acute promyelocytic leukemia (APL), French-American-British (FAB) classification M3 (including the M3 variant); For the topical treatment of acne vulgaris, flat warts and other skin conditions (psoriasis, ichthyosis congenita, icthyosis vulgaris, lamellar icthyosis, keratosis palmaris et plantaris, epidermolytic hyperkeratosis, senile comedones, senile keratosis, keratosis follicularis (Darier's disease), and basal cell carcinomas.); For palliative therapy to improve fine wrinkling, mottled hyperpigmentation, roughness associated with photodamage.
Airol Pharmacology
Tretinoin, also known as all-trans-retinoic acid (ATRA), is a naturally occurring derivative of vitamin A (retinol). Retinoids such as tretinoin are important regulators of cell reproduction, proliferation, and differentiation and are used to treat acne and photodamaged skin and to manage keratinization disorders such as ichthyosis and keratosis follicularis. Tretinoin also represents the class of anticancer drugs called differentiating agents and is used in the treatment of acute promyelocytic leukemia (APL).
Airol Absorption
1-31% (topical);
Airol Toxicity
No information avaliable
Airol Patient Information
No information avaliable
Airol Organisms Affected
Humans and other mammals
