Shin-naito_S
Category
Shin-naito_S Brand names, Shin-naito_S Analogs
Shin-naito_S Brand Names Mixture
No information avaliable
Shin-naito_S Chemical_Formula
C16H13Cl3N2OS
Shin-naito_S RX_link
http://www.rxlist.com/cgi/generic3/tioconaz.htm
Shin-naito_S fda sheet
Shin-naito_S msds (material safety sheet)
Shin-naito_S Synthesis Reference
No information avaliable
Shin-naito_S Molecular Weight
387.711 g/mol
Shin-naito_S Melting Point
No information avaliable
Shin-naito_S H2O Solubility
No information avaliable
Shin-naito_S State
Solid
Shin-naito_S LogP
4.971
Shin-naito_S Dosage Forms
Cream; Ointment; Suppository (each applicator-full provides approximately 4.6 grams of ointment containing 300 mg of tioconazole)
Shin-naito_S Indication
For the local treatment of vulvovaginal candidiasis (moniliasis).
Shin-naito_S Pharmacology
Tioconazole is a broad-spectrum imidazole antifungal agent that inhibits the growth of human pathogenic yeasts. Tioconazole exhibits fungicidal activity in vitro against Candida albicans, other species of the genus Candida, and against Torulopsis glabrata. Tioconazole prevents the growth and function of some fungal organisms by interfering with the production of substances needed to preserve the cell membrane. This drug is effective only for infections caused by fungal organisms. It will not work for bacterial or viral infections.
Shin-naito_S Absorption
Systemic absorption following a single intravaginal application of tioconazole in nonpregnant patients is negligible.
Shin-naito_S Toxicity
Symptoms of overdose include erythema, stinging, blistering, peeling, edema, pruritus, urticaria, burning,
Shin-naito_S Patient Information
Shin-naito_S Organisms Affected
Yeast and other fungi