Glupan
Category
Glupan Brand names, Glupan Analogs
Glupan Brand Names Mixture
No information avaliable
Glupan Chemical_Formula
C16H13Cl3N2OS
Glupan RX_link
http://www.rxlist.com/cgi/generic3/tioconaz.htm
Glupan fda sheet
Glupan msds (material safety sheet)
Glupan Synthesis Reference
No information avaliable
Glupan Molecular Weight
387.711 g/mol
Glupan Melting Point
No information avaliable
Glupan H2O Solubility
No information avaliable
Glupan State
Solid
Glupan LogP
4.971
Glupan Dosage Forms
Cream; Ointment; Suppository (each applicator-full provides approximately 4.6 grams of ointment containing 300 mg of tioconazole)
Glupan Indication
For the local treatment of vulvovaginal candidiasis (moniliasis).
Glupan Pharmacology
Tioconazole is a broad-spectrum imidazole antifungal agent that inhibits the growth of human pathogenic yeasts. Tioconazole exhibits fungicidal activity in vitro against Candida albicans, other species of the genus Candida, and against Torulopsis glabrata. Tioconazole prevents the growth and function of some fungal organisms by interfering with the production of substances needed to preserve the cell membrane. This drug is effective only for infections caused by fungal organisms. It will not work for bacterial or viral infections.
Glupan Absorption
Systemic absorption following a single intravaginal application of tioconazole in nonpregnant patients is negligible.
Glupan Toxicity
Symptoms of overdose include erythema, stinging, blistering, peeling, edema, pruritus, urticaria, burning,
Glupan Patient Information
Glupan Organisms Affected
Yeast and other fungi
