Sedalis_sedi-lab
Category
Sedalis_sedi-lab Brand names, Sedalis_sedi-lab Analogs
Sedalis_sedi-lab Brand Names Mixture
No information avaliable
Sedalis_sedi-lab Chemical_Formula
C16H13Cl3N2OS
Sedalis_sedi-lab RX_link
http://www.rxlist.com/cgi/generic3/tioconaz.htm
Sedalis_sedi-lab fda sheet
Sedalis_sedi-lab msds (material safety sheet)
Sedalis_sedi-lab Synthesis Reference
No information avaliable
Sedalis_sedi-lab Molecular Weight
387.711 g/mol
Sedalis_sedi-lab Melting Point
No information avaliable
Sedalis_sedi-lab H2O Solubility
No information avaliable
Sedalis_sedi-lab State
Solid
Sedalis_sedi-lab LogP
4.971
Sedalis_sedi-lab Dosage Forms
Cream; Ointment; Suppository (each applicator-full provides approximately 4.6 grams of ointment containing 300 mg of tioconazole)
Sedalis_sedi-lab Indication
For the local treatment of vulvovaginal candidiasis (moniliasis).
Sedalis_sedi-lab Pharmacology
Tioconazole is a broad-spectrum imidazole antifungal agent that inhibits the growth of human pathogenic yeasts. Tioconazole exhibits fungicidal activity in vitro against Candida albicans, other species of the genus Candida, and against Torulopsis glabrata. Tioconazole prevents the growth and function of some fungal organisms by interfering with the production of substances needed to preserve the cell membrane. This drug is effective only for infections caused by fungal organisms. It will not work for bacterial or viral infections.
Sedalis_sedi-lab Absorption
Systemic absorption following a single intravaginal application of tioconazole in nonpregnant patients is negligible.
Sedalis_sedi-lab Toxicity
Symptoms of overdose include erythema, stinging, blistering, peeling, edema, pruritus, urticaria, burning,
Sedalis_sedi-lab Patient Information
Sedalis_sedi-lab Organisms Affected
Yeast and other fungi
