Sleepan
Category
Sleepan Brand names, Sleepan Analogs
Sleepan Brand Names Mixture
No information avaliable
Sleepan Chemical_Formula
C16H13Cl3N2OS
Sleepan RX_link
http://www.rxlist.com/cgi/generic3/tioconaz.htm
Sleepan fda sheet
Sleepan msds (material safety sheet)
Sleepan Synthesis Reference
No information avaliable
Sleepan Molecular Weight
387.711 g/mol
Sleepan Melting Point
No information avaliable
Sleepan H2O Solubility
No information avaliable
Sleepan State
Solid
Sleepan LogP
4.971
Sleepan Dosage Forms
Cream; Ointment; Suppository (each applicator-full provides approximately 4.6 grams of ointment containing 300 mg of tioconazole)
Sleepan Indication
For the local treatment of vulvovaginal candidiasis (moniliasis).
Sleepan Pharmacology
Tioconazole is a broad-spectrum imidazole antifungal agent that inhibits the growth of human pathogenic yeasts. Tioconazole exhibits fungicidal activity in vitro against Candida albicans, other species of the genus Candida, and against Torulopsis glabrata. Tioconazole prevents the growth and function of some fungal organisms by interfering with the production of substances needed to preserve the cell membrane. This drug is effective only for infections caused by fungal organisms. It will not work for bacterial or viral infections.
Sleepan Absorption
Systemic absorption following a single intravaginal application of tioconazole in nonpregnant patients is negligible.
Sleepan Toxicity
Symptoms of overdose include erythema, stinging, blistering, peeling, edema, pruritus, urticaria, burning,
Sleepan Patient Information
Sleepan Organisms Affected
Yeast and other fungi