Contergan
Category
Contergan Brand names, Contergan Analogs
Contergan Brand Names Mixture
No information avaliable
Contergan Chemical_Formula
C16H13Cl3N2OS
Contergan RX_link
http://www.rxlist.com/cgi/generic3/tioconaz.htm
Contergan fda sheet
Contergan msds (material safety sheet)
Contergan Synthesis Reference
No information avaliable
Contergan Molecular Weight
387.711 g/mol
Contergan Melting Point
No information avaliable
Contergan H2O Solubility
No information avaliable
Contergan State
Solid
Contergan LogP
4.971
Contergan Dosage Forms
Cream; Ointment; Suppository (each applicator-full provides approximately 4.6 grams of ointment containing 300 mg of tioconazole)
Contergan Indication
For the local treatment of vulvovaginal candidiasis (moniliasis).
Contergan Pharmacology
Tioconazole is a broad-spectrum imidazole antifungal agent that inhibits the growth of human pathogenic yeasts. Tioconazole exhibits fungicidal activity in vitro against Candida albicans, other species of the genus Candida, and against Torulopsis glabrata. Tioconazole prevents the growth and function of some fungal organisms by interfering with the production of substances needed to preserve the cell membrane. This drug is effective only for infections caused by fungal organisms. It will not work for bacterial or viral infections.
Contergan Absorption
Systemic absorption following a single intravaginal application of tioconazole in nonpregnant patients is negligible.
Contergan Toxicity
Symptoms of overdose include erythema, stinging, blistering, peeling, edema, pruritus, urticaria, burning,
Contergan Patient Information
Contergan Organisms Affected
Yeast and other fungi
