Sedimide
Category
Sedimide Brand names, Sedimide Analogs
Sedimide Brand Names Mixture
No information avaliable
Sedimide Chemical_Formula
C16H13Cl3N2OS
Sedimide RX_link
http://www.rxlist.com/cgi/generic3/tioconaz.htm
Sedimide fda sheet
Sedimide msds (material safety sheet)
Sedimide Synthesis Reference
No information avaliable
Sedimide Molecular Weight
387.711 g/mol
Sedimide Melting Point
No information avaliable
Sedimide H2O Solubility
No information avaliable
Sedimide State
Solid
Sedimide LogP
4.971
Sedimide Dosage Forms
Cream; Ointment; Suppository (each applicator-full provides approximately 4.6 grams of ointment containing 300 mg of tioconazole)
Sedimide Indication
For the local treatment of vulvovaginal candidiasis (moniliasis).
Sedimide Pharmacology
Tioconazole is a broad-spectrum imidazole antifungal agent that inhibits the growth of human pathogenic yeasts. Tioconazole exhibits fungicidal activity in vitro against Candida albicans, other species of the genus Candida, and against Torulopsis glabrata. Tioconazole prevents the growth and function of some fungal organisms by interfering with the production of substances needed to preserve the cell membrane. This drug is effective only for infections caused by fungal organisms. It will not work for bacterial or viral infections.
Sedimide Absorption
Systemic absorption following a single intravaginal application of tioconazole in nonpregnant patients is negligible.
Sedimide Toxicity
Symptoms of overdose include erythema, stinging, blistering, peeling, edema, pruritus, urticaria, burning,
Sedimide Patient Information
Sedimide Organisms Affected
Yeast and other fungi