Polygripan
Category
Polygripan Brand names, Polygripan Analogs
Polygripan Brand Names Mixture
No information avaliable
Polygripan Chemical_Formula
C16H13Cl3N2OS
Polygripan RX_link
http://www.rxlist.com/cgi/generic3/tioconaz.htm
Polygripan fda sheet
Polygripan msds (material safety sheet)
Polygripan Synthesis Reference
No information avaliable
Polygripan Molecular Weight
387.711 g/mol
Polygripan Melting Point
No information avaliable
Polygripan H2O Solubility
No information avaliable
Polygripan State
Solid
Polygripan LogP
4.971
Polygripan Dosage Forms
Cream; Ointment; Suppository (each applicator-full provides approximately 4.6 grams of ointment containing 300 mg of tioconazole)
Polygripan Indication
For the local treatment of vulvovaginal candidiasis (moniliasis).
Polygripan Pharmacology
Tioconazole is a broad-spectrum imidazole antifungal agent that inhibits the growth of human pathogenic yeasts. Tioconazole exhibits fungicidal activity in vitro against Candida albicans, other species of the genus Candida, and against Torulopsis glabrata. Tioconazole prevents the growth and function of some fungal organisms by interfering with the production of substances needed to preserve the cell membrane. This drug is effective only for infections caused by fungal organisms. It will not work for bacterial or viral infections.
Polygripan Absorption
Systemic absorption following a single intravaginal application of tioconazole in nonpregnant patients is negligible.
Polygripan Toxicity
Symptoms of overdose include erythema, stinging, blistering, peeling, edema, pruritus, urticaria, burning,
Polygripan Patient Information
Polygripan Organisms Affected
Yeast and other fungi