lomefloxacin hydrochloride
Brand names,
lomefloxacin hydrochloride
Analogs
lomefloxacin hydrochloride
Brand Names Mixture
lomefloxacin hydrochloride
Chemical_Formula
C6H14O6
lomefloxacin hydrochloride
RX_link
http://www.rxlist.com/cgi/generic4/osmitrol.htm
lomefloxacin hydrochloride
fda sheet
lomefloxacin hydrochloride
msds (material safety sheet)
lomefloxacin hydrochloride
Synthesis Reference
No information avaliable
lomefloxacin hydrochloride
Molecular Weight
182.172 g/mol
lomefloxacin hydrochloride
Melting Point
168 oC
lomefloxacin hydrochloride
H2O Solubility
216 mg/mL
lomefloxacin hydrochloride
State
Solid
lomefloxacin hydrochloride
LogP
-3.506
lomefloxacin hydrochloride
Dosage Forms
Liquid; Powder for solution; Solution
lomefloxacin hydrochloride
Indication
Used for the promotion of diuresis before irreversible renal failure becomes established; The reduction of intracranial pressure, the treatment of cerebral edema, and the promotion of urinary excretion of toxic substances.
lomefloxacin hydrochloride
Pharmacology
Chemically, mannitol is an alcohol and a sugar, or a polyol; it is similar to xylitol or sorbitol. However, mannitol has a tendency to lose a hydrogen ion in aqueous solutions, which causes the solution to become acidic. For this reason, it is not uncommon to add a substance to adjust its pH, such as sodium bicarbonate. Mannitol is commonly used to increase urine production (diuretic). It is also used to treat or prevent medical conditions that are caused by an increase in body fluids/water (e.g., cerebral edema, glaucoma, kidney failure). Mannitol is frequently given along with other diuretics (e.g., furosemide, chlorothiazide) and/or IV fluid replacement.
lomefloxacin hydrochloride
Absorption
Approximately 7% of ingested mannitol is absorbed during gastrointestinal perfusion in uremic patients.
lomefloxacin hydrochloride
side effects and Toxicity
LD50=1700 mg/kg (rat oral)
lomefloxacin hydrochloride
Patient Information
lomefloxacin hydrochloride
Organisms Affected
Humans and other mammals