Lomefloxacinum [Latin]
Brand names,
Lomefloxacinum [Latin]
Analogs
Lomefloxacinum [Latin]
Brand Names Mixture
Lomefloxacinum [Latin]
Chemical_Formula
C6H14O6
Lomefloxacinum [Latin]
RX_link
http://www.rxlist.com/cgi/generic4/osmitrol.htm
Lomefloxacinum [Latin]
fda sheet
Lomefloxacinum [Latin]
msds (material safety sheet)
Lomefloxacinum [Latin]
Synthesis Reference
No information avaliable
Lomefloxacinum [Latin]
Molecular Weight
182.172 g/mol
Lomefloxacinum [Latin]
Melting Point
168 oC
Lomefloxacinum [Latin]
H2O Solubility
216 mg/mL
Lomefloxacinum [Latin]
State
Solid
Lomefloxacinum [Latin]
LogP
-3.506
Lomefloxacinum [Latin]
Dosage Forms
Liquid; Powder for solution; Solution
Lomefloxacinum [Latin]
Indication
Used for the promotion of diuresis before irreversible renal failure becomes established; The reduction of intracranial pressure, the treatment of cerebral edema, and the promotion of urinary excretion of toxic substances.
Lomefloxacinum [Latin]
Pharmacology
Chemically, mannitol is an alcohol and a sugar, or a polyol; it is similar to xylitol or sorbitol. However, mannitol has a tendency to lose a hydrogen ion in aqueous solutions, which causes the solution to become acidic. For this reason, it is not uncommon to add a substance to adjust its pH, such as sodium bicarbonate. Mannitol is commonly used to increase urine production (diuretic). It is also used to treat or prevent medical conditions that are caused by an increase in body fluids/water (e.g., cerebral edema, glaucoma, kidney failure). Mannitol is frequently given along with other diuretics (e.g., furosemide, chlorothiazide) and/or IV fluid replacement.
Lomefloxacinum [Latin]
Absorption
Approximately 7% of ingested mannitol is absorbed during gastrointestinal perfusion in uremic patients.
Lomefloxacinum [Latin]
side effects and Toxicity
LD50=1700 mg/kg (rat oral)
Lomefloxacinum [Latin]
Patient Information
Lomefloxacinum [Latin]
Organisms Affected
Humans and other mammals