**** MATERIAL SAFETY DATA SHEET ****
Mannitol
88721
**** SECTION 1 - CHEMICAL PRODUCT AND COMPANY IDENTIFICATION ****
MSDS Name: Mannitol
Catalog Numbers:
BP/M220, M/2400, M/2405
Synonyms:
D-Manninol, Isotol
Company Identification: Fisher Scientific UK
Bishop Meadow Road
Loughborough, Leicestershire
LE11 5RG, UK
For information, call: 01509 231166
For emergencies, call: 01509 231166
**** SECTION 2 - COMPOSITION, INFORMATION ON INGREDIENTS ****
+----------------+--------------------------------------+----------+-----------+-----------+---------------+
| CAS# | Chemical Name | % | EINECS# |Haz Symbols| Risk Phrases |
|----------------|--------------------------------------|----------|-----------|-----------|---------------+
| 69-65-8 |D-mannitol | 100% | 200-711-8 |||
+----------------+--------------------------------------+----------+-----------+-----------+---------------+
Hazard Symbols: None Listed.
Risk Phrases: None Listed.
**** SECTION 3 - HAZARDS IDENTIFICATION ****
EMERGENCY OVERVIEW
The toxicological properties of this material have not been fully
investigated.
Potential Health Effects
Eye:
May cause eye irritation.
Skin:
May cause skin irritation. Low hazard for usual industrial handling.
Ingestion:
Ingestion of large amounts may cause gastrointestinal irritation.
Expected to be a low ingestion hazard.
Inhalation:
May cause respiratory tract irritation. Low hazard for usual
industrial handling.
Chronic:
No information found.
**** SECTION 4 - FIRST AID MEASURES ****
Eyes:
Immediately flush eyes with plenty of water for at least 15 minutes,
occasionally lifting the upper and lower eyelids. Get medical aid
immediately.
Skin:
Immediately flush skin with plenty of water for at least 15 minutes
while removing contaminated clothing and shoes. Get medical aid if
irritation develops or persists.
Ingestion:
If victim is conscious and alert, give 2-4 cupfuls of milk or water.
Get medical aid immediately.
Inhalation:
Remove from exposure and move to fresh air immediately. If not
breathing, give artificial respiration. If breathing is difficult,
give oxygen. Get medical aid.
Notes to Physician:
**** SECTION 5 - FIRE FIGHTING MEASURES ****
General Information:
As in any fire, wear a self-contained breathing apparatus in
pressure-demand, MSHA/NIOSH (approved or equivalent), and full
protective gear. Dusts at sufficient concentrations can form
explosive mixtures with air.
Extinguishing Media:
For small fires, use water spray, dry chemical, carbon dioxide or
chemical foam.
**** SECTION 6 - ACCIDENTAL RELEASE MEASURES ****
General Information: Use proper personal protective equipment as indicated
in Section 8.
Spills/Leaks:
Wash area with soap and water. Clean up spills immediately,
observing precautions in the Protective Equipment section. Sweep up,
then place into a suitable container for disposal. Avoid generating
dusty conditions. Provide ventilation.
**** SECTION 7 - HANDLING and STORAGE ****
Handling:
Wash thoroughly after handling. Use with adequate ventilation. Avoid
contact with skin and eyes. Avoid ingestion and inhalation.
Storage:
Store in a cool, dry place. Keep from contact with oxidizing
materials.
**** SECTION 8 - EXPOSURE CONTROLS, PERSONAL PROTECTION ****
Engineering Controls:
Use adequate general or local exhaust ventilation to keep airborne
concentrations below the permissible exposure limits.
Personal Protective Equipment
Eyes:
Not available.
Skin:
Wear appropriate protective gloves to prevent skin
exposure.
Clothing:
Wear appropriate protective clothing to prevent skin
exposure.
Respirators:
Follow the OSHA respirator regulations found in 29
CFR 1910.134 or European Standard EN 149. Always use
a NIOSH or European Standard EN 149 approved
respirator when necessary.
**** SECTION 9 - PHYSICAL AND CHEMICAL PROPERTIES ****
Physical State: Solid
Color: white
Odor: Odorless.
pH: Not available.
Vapor Pressure: Negligible.
Viscosity: Not available.
Boiling Point: Not available.
Freezing/Melting Point: 167 deg C
Autoignition Temperature: Not available.
Flash Point: Not available.
Explosion Limits, lower: Not available.
Explosion Limits, upper: Not available.
Decomposition Temperature: Not available.
Solubility in water: Soluble in water.
Specific Gravity/Density: Not available.
Molecular Formula: C6H14O6
Molecular Weight: 182.0944
**** SECTION 10 - STABILITY AND REACTIVITY ****
Chemical Stability:
Stable under normal temperatures and pressures.
Conditions to Avoid:
Incompatible materials.
Incompatibilities with Other Materials:
Oxidizing agents.
Hazardous Decomposition Products:
Carbon monoxide, carbon dioxide.
Hazardous Polymerization: Has not been reported.
**** SECTION 11 - TOXICOLOGICAL INFORMATION ****
RTECS#:
CAS# 69-65-8: OP2060000
LD50/LC50:
CAS# 69-65-8: Oral, mouse: LD50 = 22 gm/kg; Oral, rat: LD50 = 13500
mg/kg.
Carcinogenicity:
D-mannitol -
Not listed by ACGIH, IARC, NIOSH, NTP, or OSHA.
See actual entry in RTECS for complete information.
**** SECTION 12 - ECOLOGICAL INFORMATION ****
**** SECTION 13 - DISPOSAL CONSIDERATIONS ****
Products which are considered hazardous for supply are classified as Special
Waste and the disposal of such chemicals is covered by regulations which may
vary according to location. Contact a specialist disposal company or the local
waste regulator for advice. Empty containers must be decontaminated before
returning for recycling.
**** SECTION 14 - TRANSPORT INFORMATION ****
IATA
Not regulated as a hazardous material.
IMO
Not regulated as a hazardous material.
RID/ADR
Not regulated as a hazardous material.
**** SECTION 15 - REGULATORY INFORMATION ****
European/International Regulations
European Labeling in Accordance with EC Directives
Hazard Symbols: Not available.
Risk Phrases:
Safety Phrases:
WGK (Water Danger/Protection)
CAS# 69-65-8: 0
United Kingdom Occupational Exposure Limits
United Kingdom Maximum Exposure Limits
Canada
CAS# 69-65-8 is listed on Canada's DSL List.
CAS# 69-65-8 is not listed on Canada's Ingredient Disclosure List.
Exposure Limits
US FEDERAL
TSCA
CAS# 69-65-8 is listed on the TSCA inventory.
**** SECTION 16 - ADDITIONAL INFORMATION ****
MSDS Creation Date: 6/23/2004 Revision #0 Date: Original.
The information above is believed to be accurate and represents the best
information currently available to us. However, we make no warranty of
merchantability or any other warranty, express or implied, with respect to
such information, and we assume no liability resulting from its use. Users
should make their own investigations to determine the suitability of the
information for their particular purposes. In no way shall the company be
liable for any claims, losses, or damages of any third party or for lost
profits or any special, indirect, incidental, consequential or exemplary
damages, howsoever arising, even if the company has been advised of
the possibility of such damages.
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