Maxaquin
Brand names,
Maxaquin
Analogs
Maxaquin
Brand Names Mixture
Maxaquin
Chemical_Formula
C6H14O6
Maxaquin
RX_link
http://www.rxlist.com/cgi/generic4/osmitrol.htm
Maxaquin
fda sheet
Maxaquin
msds (material safety sheet)
Maxaquin
Synthesis Reference
No information avaliable
Maxaquin
Molecular Weight
182.172 g/mol
Maxaquin
Melting Point
168 oC
Maxaquin
H2O Solubility
216 mg/mL
Maxaquin
State
Solid
Maxaquin
LogP
-3.506
Maxaquin
Dosage Forms
Liquid; Powder for solution; Solution
Maxaquin
Indication
Used for the promotion of diuresis before irreversible renal failure becomes established; The reduction of intracranial pressure, the treatment of cerebral edema, and the promotion of urinary excretion of toxic substances.
Maxaquin
Pharmacology
Chemically, mannitol is an alcohol and a sugar, or a polyol; it is similar to xylitol or sorbitol. However, mannitol has a tendency to lose a hydrogen ion in aqueous solutions, which causes the solution to become acidic. For this reason, it is not uncommon to add a substance to adjust its pH, such as sodium bicarbonate. Mannitol is commonly used to increase urine production (diuretic). It is also used to treat or prevent medical conditions that are caused by an increase in body fluids/water (e.g., cerebral edema, glaucoma, kidney failure). Mannitol is frequently given along with other diuretics (e.g., furosemide, chlorothiazide) and/or IV fluid replacement.
Maxaquin
Absorption
Approximately 7% of ingested mannitol is absorbed during gastrointestinal perfusion in uremic patients.
Maxaquin
side effects and Toxicity
LD50=1700 mg/kg (rat oral)
Maxaquin
Patient Information
Maxaquin
Organisms Affected
Humans and other mammals