LFLX en es it fr

LFLX Brand names, LFLX Analogs

LFLX Brand Names Mixture

  • No information avaliable

LFLX Chemical_Formula


LFLX RX_link


LFLX fda sheet

LFLX msds (material safety sheet)


LFLX Synthesis Reference

No information avaliable

LFLX Molecular Weight

182.172 g/mol

LFLX Melting Point

168 oC

LFLX H2O Solubility

216 mg/mL

LFLX State




LFLX Dosage Forms

Liquid; Powder for solution; Solution

LFLX Indication

Used for the promotion of diuresis before irreversible renal failure becomes established; The reduction of intracranial pressure, the treatment of cerebral edema, and the promotion of urinary excretion of toxic substances.

LFLX Pharmacology

Chemically, mannitol is an alcohol and a sugar, or a polyol; it is similar to xylitol or sorbitol. However, mannitol has a tendency to lose a hydrogen ion in aqueous solutions, which causes the solution to become acidic. For this reason, it is not uncommon to add a substance to adjust its pH, such as sodium bicarbonate. Mannitol is commonly used to increase urine production (diuretic). It is also used to treat or prevent medical conditions that are caused by an increase in body fluids/water (e.g., cerebral edema, glaucoma, kidney failure). Mannitol is frequently given along with other diuretics (e.g., furosemide, chlorothiazide) and/or IV fluid replacement.

LFLX Absorption

Approximately 7% of ingested mannitol is absorbed during gastrointestinal perfusion in uremic patients.

LFLX side effects and Toxicity

LD50=1700 mg/kg (rat oral)

LFLX Patient Information

LFLX Organisms Affected

Humans and other mammals