Categoria
CB
Marchi,
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Analoghi
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Marchi miscela
AK Spor liq (gramicidin + neomycin sulfate + polymyxin B sulfate) AK Trol Suspension (dexamethasone + neomycin sulfate + polymyxin B sulfate) Aminoderm Poudre (glycine + l-cysteine + neomycin sulfate + threonine) Anaprime oph gel (flumethasone + neomycin sulfate + polymyxin B sulfate) Bacitracin-neomycin polymyxin ont (bacitracin zinc + neomycin sulfate + polymyxin B sulfate) Bacitracin-neomycin-polymixin ont (bacitracin zinc + neomycin sulfate + polymyxin B sulfate) bacitracin-neomycin-polymyxin oph ont (bacitracin zinc + neomycin sulfate + polymyxin B sulfate) beef cattle vit ade premix medicated (neomycin sulfate + oxytetracycline hydrochloride + vitamin A + vitamin D3 + vitamin e) Biosol-M-Aquadrops liq (methscopolamine bromide + neomycin sulfate) BNPH ont (bacitracin zinc + hydrocortisone acetate + neomycin sulfate + polymyxin B sulfate) Calf scour bolus (atropine sulfate + calcium phosphate + hyoscyamine sulfate + kaolin + neomycin sulfate + pectin + sulfaguanidine + sulfathiazole + vitamin A) Certreat Scours Oblets (chlortetracycline hydrochloride + neomycin sulfate + nicotinic acid + vitamin A + vitamin D) Cicatrin Powder (bacitracin zinc + glycine + l-cysteine + neomycin sulfate + threonine) Co-op pinkeye spray (gentian violet + neomycin sulfate) Cortisporin (bacitracin zinc + hydrocortisone + neomycin sulfate + polymyxin B sulfate) Derma-4 ont (neomycin sulfate + nystatin + thiostrepton (antibiotic of a streptomyces species) + triamcinolone acetonide) Dioptrol ointment (dexamethasone + neomycin sulfate + polymyxin B sulfate) dioptrol suspension (dexamethasone + neomycin sulfate + polymyxin B sulfate) Diosporin ointment (bacitracin zinc + neomycin sulfate + polymyxin B sulfate) Enterolyte (calcium chloride dihydrate + magnesium chloride + neomycin sulfate + potassium acetate + sodium acetate + sodium chloride + sulfamethazine) FML-Neo oph sus (fluorometholone + neomycin sulfate) Forte topical suspension (hydrocortisone acetate + hydrocortisone sodium succinate + neomycin sulfate + penicillin g procaine + polymyxin B sulfate) Kaobiotic bolus (kaolin + neomycin sulfate + pectin + sulfadiazine + sulfaguanidine + sulfamerazine + sulfathiazole) Kaobiotic tab (kaolin + neomycin sulfate + pectin + sulfadiazine + sulfaguanidine + sulfamerazine + sulfathiazole) Kenacomb (gramicidin + neomycin sulfate + nystatin + triamcinolone acetonide) Keraplex spray (methyl violet + neomycin sulfate) Lidecomb cream (fluocinonide + gramicidin + neomycin sulfate + nystatin) Mastitis Care (neomycin sulfate + penicillin g potassium + polymyxin B sulfate + streptomycin sulfate) Maxitrol (dexamethasone + neomycin sulfate + polymyxin B sulfate) Mecomb Cream 0.1% (gramicidin + neomycin sulfate + nystatin + triamcinolone acetonide) Mycitracin oph ont (bacitracin + neomycin sulfate + polymyxin B sulfate) Neo Atropec 25 tab (aluminum hydroxide + atropine methylnitrate + kaolin + neomycin sulfate + pectin + sulfacetamide + sulfaguanidine) Neo Atropec C tab (aluminum hydroxide + atropine methylnitrate + kaolin + neomycin sulfate + pectin + sulfacetamide + sulfaguanidine) Neo Atropec tab (aluminum hydroxide + atropine methylnitrate + kaolin + neomycin sulfate + pectin + sulfacetamide + sulfaguanidine) Neo Chlor Powder (neomycin sulfate + tetracycline hydrochloride) Neo Darbazine Spansule Capsule no 1 (isopropamide iodide + neomycin sulfate + prochlorperazine maleate) Neo Darbazine Spansule no 3 (isopropamide iodide + neomycin sulfate + prochlorperazine maleate) Neo Oxymed Powder (neomycin sulfate + oxytetracycline hydrochloride) Neo P.P.G. (neomycin sulfate + penicillin g potassium) Neo Sulfa-E (calcium chloride + magnesium chloride + neomycin sulfate + potassium acetate + sodium acetate + sodium chloride + sulfamethazine) Neo Sulfalyte Bolus (calcium chloride + magnesium chloride + neomycin sulfate + potassium acetate + sodium acetate + sodium chloride + sulfamethazine) Neo Terramycin Soluble Powder (neomycin sulfate + oxytetracycline hydrochloride) neo-chlor (neomycin sulfate + tetracycline hydrochloride) Neo-Cortef (hydrocortisone acetate + neomycin sulfate) Neo-Medrol (methylprednisolone acetate + neomycin sulfate) Neo-Medrol Acne Lotion (aluminum chlorohydrate + methylprednisolone acetate + neomycin sulfate + sulfur) Neo-Oxytetracycline (neomycin sulfate + oxytetracycline hydrochloride) Neo-Terramycin 50/50 premix (neomycin sulfate + oxytetracycline hydrochloride) Neo-Tet pws (neomycin sulfate + oxytetracycline hydrochloride) Neodecadron Eye Ear Solution 0.1% (dexamethasone phosphate + neomycin sulfate) Neomix-Pamine Solution (methscopolamine bromide + neomycin sulfate) Neopaste (aluminum hydroxide + calcium chloride + magnesium chloride + neomycin sulfate + potassium acetate + sodium acetate + sodium chloride + sulfamethazine + sulfathiazole) Neorease (neomycin sulfate + sulfamethazine + sulfathiazole) Neosol M Aquadrops (methscopolamine bromide + neomycin sulfate) Neospan Mastitis Treatment (neomycin sulfate + penicillin g potassium + polymyxin B sulfate + streptomycin sulfate) Neosporin antibiotic cream (gramicidin + neomycin sulfate + polymyxin B sulfate) Neosporin Eye-Ear Solution (gramicidin + neomycin sulfate + polymyxin B sulfate) Neosporin Irrigating Solution (neomycin sulfate + polymyxin B sulfate) Neosporin Ointment (bacitracin zinc + neomycin sulfate + polymyxin B sulfate) Neosporin Ophthalmic Ointment (bacitracin zinc + neomycin sulfate + polymyxin B sulfate) Neosulf (neomycin sulfate + sulfamethazine + sulfathiazole) Neosulf bolus (calcium chloride + magnesium chloride + neomycin sulfate + potassium acetate + sodium acetate + sodium chloride + sulfamethazine) Neosulf Plus bolus (calcium chloride + magnesium chloride + neomycin sulfate + potassium acetate + sodium acetate + sodium chloride + sulfamethazine) Neosulpec (kaolin + neomycin + pectin + sulfaguanidine + sulfamethazine + sulfathiazole) Neotet soluble concentrate (neomycin sulfate + oxytetracycline hydrochloride) Neotetramed Powder (neomycin sulfate + tetracycline hydrochloride) Neotopic ointment (bacitracin zinc + neomycin sulfate + polymyxin B sulfate) Neovast tabs (kaolin + neomycin sulfate + pectin + sulfadiazine + sulfaguanidine + sulfamerazine + sulfathiazole) Neox (neomycin sulfate + oxytetracycline hydrochloride) Ophtacin ophtalmic ointment (bacitracin zinc + neomycin sulfate + polymyxin B sulfate) Ophtacin-H ophtalmic ointment (bacitracin zinc + hydrocortisone acetate + neomycin sulfate + polymyxin B sulfate) Optimyxin Plus Oto-opht GTTE (gramicidin + neomycin sulfate + polymyxin B sulfate) Optiprime oph gel (neomycin sulfate + polymyxin B sulfate) Optisone (neomycin + prednisolone) Oribiotic ointment (bacitracin + lidocaine + neomycin sulfate + nystatin + triamcinolone acetonide) Otizol HC liq (hydrocortisone acetate + lidocaine hydrochloride + neomycin sulfate) P.T. Booster (calcium d-pantothenate + neomycin sulfate + nicotinic acid + pyridoxine hydrochloride + streptomycin sulfate + vitamin A + vitamin B1 + vitamin B12 + vitamin B2 + vitamin D3) Panolog cream (neomycin sulfate + nystatin + thiostrepton [antibiotic of a streptomyces species] + triamcinolone acetonide) Panolog ointment (neomycin sulfate + nystatin + thiostrepton [antibiotic of a streptomyces species] + triamcinolone acetonide) Pinkeye Spray (gentian violet + neomycin sulfate) Previte (neomycin sulfate + selenium sulfide + streptomycin sulfate + vitamin A + vitamin D + vitamin e + vitamin K1) Proctosone ont (dibucaine hydrochloride + esculin + hydrocortisone acetate + neomycin sulfate) Proctosone sup (dibucaine hydrochloride + esculin + hydrocortisone acetate + neomycin sulfate) Ratio-Triacomb regular cream (gramicidin + neomycin sulfate + nystatin + triamcinolone acetonide) Sandoz Cortimyxin (bacitracin zinc + hydrocortisone + neomycin sulfate + polymyxin B sulfate) Scour bolus plus (calcium carbonate + magnesium oxide + menadione sodium bisulfite + neomycin sulfate + potassium acetate + sodium acetate + sodium chloride + streptomycin sulfate + sulfamerazine + sulfamethazine + sulfanilamide + sulfathiazole + vitamin A + vitamin D) Scour Solution (methscopolamine bromide + neomycin sulfate) Scour solution coop (methscopolamine bromide + neomycin sulfate) Scour suspension (atropine sulfate + calcium phosphate + hyoscyamine sulfate + kaolin + neomycin sulfate + pectin + succinylsulfathiazole) Scour treat liq (neomycin sulfate + sulfamethazine + sulfathiazole) Scour-plug (calcium chloride + magnesium chloride + neomycin sulfate + potassium acetate + sodium acetate + sodium chloride + sulfamethazine) Septomixine Forte (dexamethasone + halethazole tartrate + neomycin sulfate + polymyxin B sulfate + tyrothricin) Solvaderm ointment (neomycin sulfate + nystatin + thiostrepton [antibiotic of a streptomyces species] + triamcinolone acetonide) Spor-HC otic susp (hydrocortisone + neomycin sulfate + polymyxin B sulfate) Sulectim plus scour boluses (calcium carbonate + magnesium oxide + menadione sodium bisulfite + neomycin sulfate + potassium acetate + sodium acetate + sodium chloride + streptomycin sulfate + sulfamerazine + sulfamethazine + sulfanilamide + sulfathiazole sodium + vitamin A + vitamin D) Sulkamycin S Bolettes (neomycin sulfate + sulfamethazine) Synalar Bi-otic solution (fluocinolone acetonide + neomycin sulfate + polymyxin B sulfate) Theraderm cream (gramicidin + neomycin sulfate + nystatin + triamcinolone acetonide) Tresaderm dermatologic solution (dexamethasone + neomycin sulfate + thiabendazole) Triple sulfa plus neomycin (neomycin sulfate + sulfamerazine sodium + sulfamethazine sodium + sulfathiazole sodium) Vetropolycin HC ont (bacitracin zinc + hydrocortisone acetate + neomycin sulfate + polymyxin B) Vetropolycin ont (bacitracin zinc + neomycin sulfate + polymyxin B sulfate) Viaderm KC Cream (gramicidin + neomycin sulfate + nystatin + triamcinolone acetonide) Viaderm KC ont (gramicidin + neomycin sulfate + nystatin + triamcinolone acetonide) Wound & Pinkeye Spray (gentian violet + neomycin sulfate)
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Formula chimica
C23H46N6O13
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RX link
http://www.rxlist.com/cgi/generic3/neomy.htm
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FDA foglio
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DMS (foglio di materiale di sicurezza)
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Sintesi di riferimento
Nessuna informazione disponibile
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Peso molecolare
614.644 g/mol
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Temperatura di fusione
6 mg/mL (as sulfate form)
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H2O Solubilita
Nessuna informazione disponibile
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Stato
Solid
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LogP
-9.895
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Forme di dosaggio
Polvere
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Indicazione
Per il trattamento aggiuntivo di insufficienza epatica acuta, cirrosi alcolica del fegato, e la soppressione dei batteri intestinali.
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Farmacologia
Neomicina è un antibiotico aminoglicoside. Aminoglicosidi agiscono legandosi alla subunità ribosomiale batterica 30S, provocando lettura erronea di t-RNA, lasciando il batterio in grado di sintetizzare proteine vitale alla sua crescita. Aminoglicosidi sono utili soprattutto in infezioni che coinvolgono aerobica, batteri Gram-negativi, come Pseudomonas, Acinetobacter, e Enterobacter. Inoltre, alcuni micobatteri, tra cui i batteri che causano la tubercolosi, sono sensibili agli aminoglicosidi. Infezioni causate da batteri Gram-positivi batteri possono anche essere trattati con aminoglicosidi, ma altri tipi di antibiotici sono più potenti e meno dannose per l'host. In passato gli aminoglicosidi sono stati utilizzati in congiunzione con penicillina connessi antibiotici per le infezioni da streptococco per i loro effetti sinergici, in particolare di endocardite. Gli aminoglicosidi sono per lo più inefficaci contro i batteri anaerobici, funghi e virus.
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Assorbimento
Scarsamente assorbito dal tratto gastrointestinale normale. Anche se solo circa il 3% di neomicina è assorbito attraverso la mucosa intestinale intatta, quantità significative possono essere assorbiti attraverso la mucosa ulcerata o denudato, o se l'infiammazione è presente.
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Tossicita
LD50 = 200 mg / kg (ratto). A causa del basso assorbimento, è improbabile che il sovradosaggio acuto accadrebbe con neomicina orale. Tuttavia, la somministrazione prolungata potrebbe causare sufficienti livelli di farmaci sistemici per la produzione di neurotossicità, ototossicità e / o nefrotossicità.
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Informazioni paziente
Before administering the drug, patients or members of their families should be informed of possible toxic effects
on the eighth nerve. The possibility of acute toxicity increases in premature infants and neonates.
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Atto interessato organismi
Batteri enterici e altri eubatteri
