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Zyban Brand names, Zyban Analogs

Zyban Brand Names Mixture

  • No information avaliable

Zyban Chemical_Formula


Zyban RX_link


Zyban fda sheet

Zyban FDA

Zyban msds (material safety sheet)

Zyban Synthesis Reference

N. B. Mehta, U.S. Pat.. 3,819,706 and 3,885,046 (1974,1975)

Zyban Molecular Weight

239.741 g/mol

Zyban Melting Point


Zyban H2O Solubility

312 mg/ml

Zyban State


Zyban LogP


Zyban Dosage Forms

Immediate and sustained release tablets

Zyban Indication

For the treatment of depression and as aid to smoking cessation.

Zyban Pharmacology

Bupropion, an antidepressant of the aminoketone class and a non-nicotine aid to smoking cessation, is chemically unrelated to tricyclic, tetracyclic, selective serotonin re-uptake inhibitor, or other known antidepressant agents. Compared to classical tricyclic antidepressants, Bupropion is a relatively weak inhibitor of the neuronal uptake of norepinephrine, serotonin, and dopamine. In addition, Bupropion does not inhibit monoamine oxidase. Bupropion produces dose-related central nervous system (CNS) stimulant effects in animals, as evidenced by increased locomotor activity, increased rates of responding in various schedule-controlled operant behavior tasks, and, at high doses, induction of mild stereotyped behavior.

Zyban Absorption

For sustained release, peak plasma concentrations are achieved within 3 hours.

Zyban side effects and Toxicity

Symptoms of overdose include seizures, hallucinations, loss of consciousness, tachycardia, and cardiac arrest.

Zyban Patient Information

Zyban Organisms Affected

Humans and other mammals