Wellbatrin
Brand names,
Wellbatrin
Analogs
Wellbatrin
Brand Names Mixture
Wellbatrin
Chemical_Formula
C13H18ClNO
Wellbatrin
RX_link
http://www.rxlist.com/cgi/generic/bupropz.htm
Wellbatrin
fda sheet
Wellbatrin
msds (material safety sheet)
Wellbatrin
Synthesis Reference
N. B. Mehta, U.S. Pat.. 3,819,706 and 3,885,046 (1974,1975)
Wellbatrin
Molecular Weight
239.741 g/mol
Wellbatrin
Melting Point
233-234oC
Wellbatrin
H2O Solubility
312 mg/ml
Wellbatrin
State
Solid
Wellbatrin
LogP
3.741
Wellbatrin
Dosage Forms
Immediate and sustained release tablets
Wellbatrin
Indication
For the treatment of depression and as aid to smoking cessation.
Wellbatrin
Pharmacology
Bupropion, an antidepressant of the aminoketone class and a non-nicotine aid to smoking cessation, is chemically unrelated to tricyclic, tetracyclic, selective serotonin re-uptake inhibitor, or other known antidepressant agents. Compared to classical tricyclic antidepressants, Bupropion is a relatively weak inhibitor of the neuronal uptake of norepinephrine, serotonin, and dopamine. In addition, Bupropion does not inhibit monoamine oxidase. Bupropion produces dose-related central nervous system (CNS) stimulant effects in animals, as evidenced by increased locomotor activity, increased rates of responding in various schedule-controlled operant behavior tasks, and, at high doses, induction of mild stereotyped behavior.
Wellbatrin
Absorption
For sustained release, peak plasma concentrations are achieved within 3 hours.
Wellbatrin
side effects and Toxicity
Symptoms of overdose include seizures, hallucinations, loss of consciousness, tachycardia, and cardiac arrest.
Wellbatrin
Patient Information
Wellbatrin
Organisms Affected
Humans and other mammals