Wellbutrin Xl

• Antidepressants
• ATC:N07BA02

• Bupropion Hcl
• Wellbatrin
• Wellbutrin
• Wellbutrin Sr
• Wellbutrin Xl
• Zyban

• No information avaliable

C₁₃H₁₈ClNO

http://www.rxlist.com/cgi/generic/bupropz.htm

Wellbutrin_Xl FDA

N. B. Mehta, U.S. Pat.. 3,819,706 and 3,885,046 (1974,1975)

239.741 g/mol

233-234^oC

312 mg/ml

Solid

3.741

Immediate and sustained release tablets

For the treatment of depression and as aid to smoking cessation.

Bupropion, an antidepressant of the aminoketone class and a non-nicotine aid to smoking cessation, is chemically unrelated to tricyclic, tetracyclic, selective serotonin re-uptake inhibitor, or other known antidepressant agents. Compared to classical tricyclic antidepressants, Bupropion is a relatively weak inhibitor of the neuronal uptake of norepinephrine, serotonin, and dopamine. In addition, Bupropion does not inhibit monoamine oxidase. Bupropion produces dose-related central nervous system (CNS) stimulant effects in animals, as evidenced by increased locomotor activity, increased rates of responding in various schedule-controlled operant behavior tasks, and, at high doses, induction of mild stereotyped behavior.

For sustained release, peak plasma concentrations are achieved within 3 hours.

Symptoms of overdose include seizures, hallucinations, loss of consciousness, tachycardia, and cardiac arrest.

Humans and other mammals