Wellbutrin Xl
Brand names,
Wellbutrin Xl
Analogs
Wellbutrin Xl
Brand Names Mixture
Wellbutrin Xl
Chemical_Formula
C13H18ClNO
Wellbutrin Xl
RX_link
http://www.rxlist.com/cgi/generic/bupropz.htm
Wellbutrin Xl
fda sheet
Wellbutrin Xl
msds (material safety sheet)
Wellbutrin Xl
Synthesis Reference
N. B. Mehta, U.S. Pat.. 3,819,706 and 3,885,046 (1974,1975)
Wellbutrin Xl
Molecular Weight
239.741 g/mol
Wellbutrin Xl
Melting Point
233-234oC
Wellbutrin Xl
H2O Solubility
312 mg/ml
Wellbutrin Xl
State
Solid
Wellbutrin Xl
LogP
3.741
Wellbutrin Xl
Dosage Forms
Immediate and sustained release tablets
Wellbutrin Xl
Indication
For the treatment of depression and as aid to smoking cessation.
Wellbutrin Xl
Pharmacology
Bupropion, an antidepressant of the aminoketone class and a non-nicotine aid to smoking cessation, is chemically unrelated to tricyclic, tetracyclic, selective serotonin re-uptake inhibitor, or other known antidepressant agents. Compared to classical tricyclic antidepressants, Bupropion is a relatively weak inhibitor of the neuronal uptake of norepinephrine, serotonin, and dopamine. In addition, Bupropion does not inhibit monoamine oxidase. Bupropion produces dose-related central nervous system (CNS) stimulant effects in animals, as evidenced by increased locomotor activity, increased rates of responding in various schedule-controlled operant behavior tasks, and, at high doses, induction of mild stereotyped behavior.
Wellbutrin Xl
Absorption
For sustained release, peak plasma concentrations are achieved within 3 hours.
Wellbutrin Xl
side effects and Toxicity
Symptoms of overdose include seizures, hallucinations, loss of consciousness, tachycardia, and cardiac arrest.
Wellbutrin Xl
Patient Information
Wellbutrin Xl
Organisms Affected
Humans and other mammals