Bupropion Hcl
Bupropion Hcl Brand names, Bupropion Hcl Analogs
Bupropion Hcl Brand Names Mixture
- No information avaliable
Bupropion Hcl Chemical_Formula
C13H18ClNO
Bupropion Hcl RX_link
http://www.rxlist.com/cgi/generic/bupropz.htm
Bupropion Hcl fda sheet
Bupropion Hcl msds (material safety sheet)
Bupropion Hcl Synthesis Reference
N. B. Mehta, U.S. Pat.. 3,819,706 and 3,885,046 (1974,1975)
Bupropion Hcl Molecular Weight
239.741 g/mol
Bupropion Hcl Melting Point
233-234oC
Bupropion Hcl H2O Solubility
312 mg/ml
Bupropion Hcl State
Solid
Bupropion Hcl LogP
3.741
Bupropion Hcl Dosage Forms
Immediate and sustained release tablets
Bupropion Hcl Indication
For the treatment of depression and as aid to smoking cessation.
Bupropion Hcl Pharmacology
Bupropion, an antidepressant of the aminoketone class and a non-nicotine aid to smoking cessation, is chemically unrelated to tricyclic, tetracyclic, selective serotonin re-uptake inhibitor, or other known antidepressant agents. Compared to classical tricyclic antidepressants, Bupropion is a relatively weak inhibitor of the neuronal uptake of norepinephrine, serotonin, and dopamine. In addition, Bupropion does not inhibit monoamine oxidase. Bupropion produces dose-related central nervous system (CNS) stimulant effects in animals, as evidenced by increased locomotor activity, increased rates of responding in various schedule-controlled operant behavior tasks, and, at high doses, induction of mild stereotyped behavior.
Bupropion Hcl Absorption
For sustained release, peak plasma concentrations are achieved within 3 hours.
Bupropion Hcl side effects and Toxicity
Symptoms of overdose include seizures, hallucinations, loss of consciousness, tachycardia, and cardiac arrest.
Bupropion Hcl Patient Information
Bupropion Hcl Organisms Affected
Humans and other mammals
