Wellbutrin
Wellbutrin Brand names, Wellbutrin Analogs
Wellbutrin Brand Names Mixture
- No information avaliable
Wellbutrin Chemical_Formula
C13H18ClNO
Wellbutrin RX_link
http://www.rxlist.com/cgi/generic/bupropz.htm
Wellbutrin fda sheet
Wellbutrin msds (material safety sheet)
Wellbutrin Synthesis Reference
N. B. Mehta, U.S. Pat.. 3,819,706 and 3,885,046 (1974,1975)
Wellbutrin Molecular Weight
239.741 g/mol
Wellbutrin Melting Point
233-234oC
Wellbutrin H2O Solubility
312 mg/ml
Wellbutrin State
Solid
Wellbutrin LogP
3.741
Wellbutrin Dosage Forms
Immediate and sustained release tablets
Wellbutrin Indication
For the treatment of depression and as aid to smoking cessation.
Wellbutrin Pharmacology
Bupropion, an antidepressant of the aminoketone class and a non-nicotine aid to smoking cessation, is chemically unrelated to tricyclic, tetracyclic, selective serotonin re-uptake inhibitor, or other known antidepressant agents. Compared to classical tricyclic antidepressants, Bupropion is a relatively weak inhibitor of the neuronal uptake of norepinephrine, serotonin, and dopamine. In addition, Bupropion does not inhibit monoamine oxidase. Bupropion produces dose-related central nervous system (CNS) stimulant effects in animals, as evidenced by increased locomotor activity, increased rates of responding in various schedule-controlled operant behavior tasks, and, at high doses, induction of mild stereotyped behavior.
Wellbutrin Absorption
For sustained release, peak plasma concentrations are achieved within 3 hours.
Wellbutrin side effects and Toxicity
Symptoms of overdose include seizures, hallucinations, loss of consciousness, tachycardia, and cardiac arrest.
Wellbutrin Patient Information
Wellbutrin Organisms Affected
Humans and other mammals
