Tizanidine
Brand names,
Tizanidine
Analogs
Tizanidine
Brand Names Mixture
Tizanidine
Chemical_Formula
C9H8ClN5S
Tizanidine
RX_link
http://www.rxlist.com/cgi/generic/tizanidine.htm
Tizanidine
fda sheet
Tizanidine
msds (material safety sheet)
Tizanidine
Synthesis Reference
No information avaliable
Tizanidine
Molecular Weight
253.712 g/mol
Tizanidine
Melting Point
No information avaliable
Tizanidine
H2O Solubility
No information avaliable
Tizanidine
State
Solid
Tizanidine
LogP
-1.591
Tizanidine
Dosage Forms
Tablet
Tizanidine
Indication
For the management of increased muscle tone associated with spasticity
Tizanidine
Pharmacology
Tizanidine is a short-acting drug for the management of spasticity. Tizanidine is an agonist at a2-adrenergic receptor sites and presumably reduces spasticity by increasing presynaptic inhibition of motor neurons. In animal models, tizanidine has no direct effect on skeletal muscle fibers or the neuromuscular junction, and no major effect on monosynaptic spinal reflexes. The effects of tizanidine are greatest on polysynaptic pathways. The overall effect of these actions is thought to reduce facilitation of spinal motor neurons.
Tizanidine
Absorption
No information avaliable
Tizanidine
side effects and Toxicity
No information avaliable
Tizanidine
Patient Information
No information avaliable
Tizanidine
Organisms Affected
Humans and other mammals