Tizanidine Hcl
Brand names,
Tizanidine Hcl
Analogs
Tizanidine Hcl
Brand Names Mixture
Tizanidine Hcl
Chemical_Formula
C9H8ClN5S
Tizanidine Hcl
RX_link
http://www.rxlist.com/cgi/generic/tizanidine.htm
Tizanidine Hcl
fda sheet
Tizanidine Hcl
msds (material safety sheet)
Tizanidine Hcl
Synthesis Reference
No information avaliable
Tizanidine Hcl
Molecular Weight
253.712 g/mol
Tizanidine Hcl
Melting Point
No information avaliable
Tizanidine Hcl
H2O Solubility
No information avaliable
Tizanidine Hcl
State
Solid
Tizanidine Hcl
LogP
-1.591
Tizanidine Hcl
Dosage Forms
Tablet
Tizanidine Hcl
Indication
For the management of increased muscle tone associated with spasticity
Tizanidine Hcl
Pharmacology
Tizanidine is a short-acting drug for the management of spasticity. Tizanidine is an agonist at a2-adrenergic receptor sites and presumably reduces spasticity by increasing presynaptic inhibition of motor neurons. In animal models, tizanidine has no direct effect on skeletal muscle fibers or the neuromuscular junction, and no major effect on monosynaptic spinal reflexes. The effects of tizanidine are greatest on polysynaptic pathways. The overall effect of these actions is thought to reduce facilitation of spinal motor neurons.
Tizanidine Hcl
Absorption
No information avaliable
Tizanidine Hcl
side effects and Toxicity
No information avaliable
Tizanidine Hcl
Patient Information
No information avaliable
Tizanidine Hcl
Organisms Affected
Humans and other mammals