Tizanidinum [Inn-Latin]
Brand names,
Tizanidinum [Inn-Latin]
Analogs
Tizanidinum [Inn-Latin]
Brand Names Mixture
Tizanidinum [Inn-Latin]
Chemical_Formula
C9H8ClN5S
Tizanidinum [Inn-Latin]
RX_link
http://www.rxlist.com/cgi/generic/tizanidine.htm
Tizanidinum [Inn-Latin]
fda sheet
Tizanidinum [Inn-Latin]
msds (material safety sheet)
Tizanidinum [Inn-Latin]
Synthesis Reference
No information avaliable
Tizanidinum [Inn-Latin]
Molecular Weight
253.712 g/mol
Tizanidinum [Inn-Latin]
Melting Point
No information avaliable
Tizanidinum [Inn-Latin]
H2O Solubility
No information avaliable
Tizanidinum [Inn-Latin]
State
Solid
Tizanidinum [Inn-Latin]
LogP
-1.591
Tizanidinum [Inn-Latin]
Dosage Forms
Tablet
Tizanidinum [Inn-Latin]
Indication
For the management of increased muscle tone associated with spasticity
Tizanidinum [Inn-Latin]
Pharmacology
Tizanidine is a short-acting drug for the management of spasticity. Tizanidine is an agonist at a2-adrenergic receptor sites and presumably reduces spasticity by increasing presynaptic inhibition of motor neurons. In animal models, tizanidine has no direct effect on skeletal muscle fibers or the neuromuscular junction, and no major effect on monosynaptic spinal reflexes. The effects of tizanidine are greatest on polysynaptic pathways. The overall effect of these actions is thought to reduce facilitation of spinal motor neurons.
Tizanidinum [Inn-Latin]
Absorption
No information avaliable
Tizanidinum [Inn-Latin]
side effects and Toxicity
No information avaliable
Tizanidinum [Inn-Latin]
Patient Information
No information avaliable
Tizanidinum [Inn-Latin]
Organisms Affected
Humans and other mammals