Sirdalud
Brand names,
Sirdalud
Analogs
Sirdalud
Brand Names Mixture
Sirdalud
Chemical_Formula
C9H8ClN5S
Sirdalud
RX_link
http://www.rxlist.com/cgi/generic/tizanidine.htm
Sirdalud
fda sheet
Sirdalud
msds (material safety sheet)
Sirdalud
Synthesis Reference
No information avaliable
Sirdalud
Molecular Weight
253.712 g/mol
Sirdalud
Melting Point
No information avaliable
Sirdalud
H2O Solubility
No information avaliable
Sirdalud
State
Solid
Sirdalud
LogP
-1.591
Sirdalud
Dosage Forms
Tablet
Sirdalud
Indication
For the management of increased muscle tone associated with spasticity
Sirdalud
Pharmacology
Tizanidine is a short-acting drug for the management of spasticity. Tizanidine is an agonist at a2-adrenergic receptor sites and presumably reduces spasticity by increasing presynaptic inhibition of motor neurons. In animal models, tizanidine has no direct effect on skeletal muscle fibers or the neuromuscular junction, and no major effect on monosynaptic spinal reflexes. The effects of tizanidine are greatest on polysynaptic pathways. The overall effect of these actions is thought to reduce facilitation of spinal motor neurons.
Sirdalud
Absorption
No information avaliable
Sirdalud
side effects and Toxicity
No information avaliable
Sirdalud
Patient Information
No information avaliable
Sirdalud
Organisms Affected
Humans and other mammals