Tizanidina [Inn-Spanish]
Brand names,
Tizanidina [Inn-Spanish]
Analogs
Tizanidina [Inn-Spanish]
Brand Names Mixture
Tizanidina [Inn-Spanish]
Chemical_Formula
C9H8ClN5S
Tizanidina [Inn-Spanish]
RX_link
http://www.rxlist.com/cgi/generic/tizanidine.htm
Tizanidina [Inn-Spanish]
fda sheet
Tizanidina [Inn-Spanish]
msds (material safety sheet)
Tizanidina [Inn-Spanish]
Synthesis Reference
No information avaliable
Tizanidina [Inn-Spanish]
Molecular Weight
253.712 g/mol
Tizanidina [Inn-Spanish]
Melting Point
No information avaliable
Tizanidina [Inn-Spanish]
H2O Solubility
No information avaliable
Tizanidina [Inn-Spanish]
State
Solid
Tizanidina [Inn-Spanish]
LogP
-1.591
Tizanidina [Inn-Spanish]
Dosage Forms
Tablet
Tizanidina [Inn-Spanish]
Indication
For the management of increased muscle tone associated with spasticity
Tizanidina [Inn-Spanish]
Pharmacology
Tizanidine is a short-acting drug for the management of spasticity. Tizanidine is an agonist at a2-adrenergic receptor sites and presumably reduces spasticity by increasing presynaptic inhibition of motor neurons. In animal models, tizanidine has no direct effect on skeletal muscle fibers or the neuromuscular junction, and no major effect on monosynaptic spinal reflexes. The effects of tizanidine are greatest on polysynaptic pathways. The overall effect of these actions is thought to reduce facilitation of spinal motor neurons.
Tizanidina [Inn-Spanish]
Absorption
No information avaliable
Tizanidina [Inn-Spanish]
side effects and Toxicity
No information avaliable
Tizanidina [Inn-Spanish]
Patient Information
No information avaliable
Tizanidina [Inn-Spanish]
Organisms Affected
Humans and other mammals