Zanaflex
Brand names,
Zanaflex
Analogs
Zanaflex
Brand Names Mixture
Zanaflex
Chemical_Formula
C9H8ClN5S
Zanaflex
RX_link
http://www.rxlist.com/cgi/generic/tizanidine.htm
Zanaflex
fda sheet
Zanaflex
msds (material safety sheet)
Zanaflex
Synthesis Reference
No information avaliable
Zanaflex
Molecular Weight
253.712 g/mol
Zanaflex
Melting Point
No information avaliable
Zanaflex
H2O Solubility
No information avaliable
Zanaflex
State
Solid
Zanaflex
LogP
-1.591
Zanaflex
Dosage Forms
Tablet
Zanaflex
Indication
For the management of increased muscle tone associated with spasticity
Zanaflex
Pharmacology
Tizanidine is a short-acting drug for the management of spasticity. Tizanidine is an agonist at a2-adrenergic receptor sites and presumably reduces spasticity by increasing presynaptic inhibition of motor neurons. In animal models, tizanidine has no direct effect on skeletal muscle fibers or the neuromuscular junction, and no major effect on monosynaptic spinal reflexes. The effects of tizanidine are greatest on polysynaptic pathways. The overall effect of these actions is thought to reduce facilitation of spinal motor neurons.
Zanaflex
Absorption
No information avaliable
Zanaflex
side effects and Toxicity
No information avaliable
Zanaflex
Patient Information
No information avaliable
Zanaflex
Organisms Affected
Humans and other mammals