Terbinafine hydrochloride
Brand names,
Terbinafine hydrochloride
Analogs
Terbinafine hydrochloride
Brand Names Mixture
Terbinafine hydrochloride
Chemical_Formula
C21H25N
Terbinafine hydrochloride
RX_link
http://www.rxlist.com/cgi/generic/terbin.htm
Terbinafine hydrochloride
fda sheet
Terbinafine hydrochloride
msds (material safety sheet)
Terbinafine hydrochloride
Synthesis Reference
A. Stutz, Eur. pat. Appl. 24,587 (1981 to Sandoz)
Terbinafine hydrochloride
Molecular Weight
291.43 g/mol
Terbinafine hydrochloride
Melting Point
195-198 oC
Terbinafine hydrochloride
H2O Solubility
Slightly soluble
Terbinafine hydrochloride
State
Solid
Terbinafine hydrochloride
LogP
6.466
Terbinafine hydrochloride
Dosage Forms
Tablet; Cream; Spray
Terbinafine hydrochloride
Indication
For the treatment of interdigital tinea infections.
Terbinafine hydrochloride
Pharmacology
Terbinafine is an allylamine antifungal agent and acts by inhibiting squalene epoxidase, thus blocking the biosynthesis of ergosterol, an essential component of fungal cell membranes. in vitro, mammalian squalene epoxidase is only inhibited at higher (4000 fold) concentrations than is needed for inhibition of the dermatophyte enzyme. Depending on the concentration of the drug and the fungal species test in vitro, Terbinafine may be fungicidal. However, the clinical significance of in vitro data is unknown.
Terbinafine hydrochloride
Absorption
Readily absorbed from gastrointestinal tract.
Terbinafine hydrochloride
side effects and Toxicity
No information avaliable
Terbinafine hydrochloride
Patient Information
Patient Information:
Discuss with you doctor about the risks of this medication before taking it.
Do not dring alcohol while you are taking Terbinafine, because liber problem may
occur. Contack you doctor if you experience any discomforts, for example, nausea, vomiting, loss of appetite,
yellow eys or skin.
Finsh the medication even if you feel better.
Terbinafine hydrochloride
Organisms Affected
Fungi