Terbinafine HCl
Brand names,
Terbinafine HCl
Analogs
Terbinafine HCl
Brand Names Mixture
Terbinafine HCl
Chemical_Formula
C21H25N
Terbinafine HCl
RX_link
http://www.rxlist.com/cgi/generic/terbin.htm
Terbinafine HCl
fda sheet
Terbinafine HCl
msds (material safety sheet)
Terbinafine HCl
Synthesis Reference
A. Stutz, Eur. pat. Appl. 24,587 (1981 to Sandoz)
Terbinafine HCl
Molecular Weight
291.43 g/mol
Terbinafine HCl
Melting Point
195-198 oC
Terbinafine HCl
H2O Solubility
Slightly soluble
Terbinafine HCl
State
Solid
Terbinafine HCl
LogP
6.466
Terbinafine HCl
Dosage Forms
Tablet; Cream; Spray
Terbinafine HCl
Indication
For the treatment of interdigital tinea infections.
Terbinafine HCl
Pharmacology
Terbinafine is an allylamine antifungal agent and acts by inhibiting squalene epoxidase, thus blocking the biosynthesis of ergosterol, an essential component of fungal cell membranes. in vitro, mammalian squalene epoxidase is only inhibited at higher (4000 fold) concentrations than is needed for inhibition of the dermatophyte enzyme. Depending on the concentration of the drug and the fungal species test in vitro, Terbinafine may be fungicidal. However, the clinical significance of in vitro data is unknown.
Terbinafine HCl
Absorption
Readily absorbed from gastrointestinal tract.
Terbinafine HCl
side effects and Toxicity
No information avaliable
Terbinafine HCl
Patient Information
Patient Information:
Discuss with you doctor about the risks of this medication before taking it.
Do not dring alcohol while you are taking Terbinafine, because liber problem may
occur. Contack you doctor if you experience any discomforts, for example, nausea, vomiting, loss of appetite,
yellow eys or skin.
Finsh the medication even if you feel better.
Terbinafine HCl
Organisms Affected
Fungi