Bramazil
Brand names,
Bramazil
Analogs
Bramazil
Brand Names Mixture
Bramazil
Chemical_Formula
C21H25N
Bramazil
RX_link
http://www.rxlist.com/cgi/generic/terbin.htm
Bramazil
fda sheet
Bramazil
msds (material safety sheet)
Bramazil
Synthesis Reference
A. Stutz, Eur. pat. Appl. 24,587 (1981 to Sandoz)
Bramazil
Molecular Weight
291.43 g/mol
Bramazil
Melting Point
195-198 oC
Bramazil
H2O Solubility
Slightly soluble
Bramazil
State
Solid
Bramazil
LogP
6.466
Bramazil
Dosage Forms
Tablet; Cream; Spray
Bramazil
Indication
For the treatment of interdigital tinea infections.
Bramazil
Pharmacology
Terbinafine is an allylamine antifungal agent and acts by inhibiting squalene epoxidase, thus blocking the biosynthesis of ergosterol, an essential component of fungal cell membranes. in vitro, mammalian squalene epoxidase is only inhibited at higher (4000 fold) concentrations than is needed for inhibition of the dermatophyte enzyme. Depending on the concentration of the drug and the fungal species test in vitro, Terbinafine may be fungicidal. However, the clinical significance of in vitro data is unknown.
Bramazil
Absorption
Readily absorbed from gastrointestinal tract.
Bramazil
side effects and Toxicity
No information avaliable
Bramazil
Patient Information
Patient Information:
Discuss with you doctor about the risks of this medication before taking it.
Do not dring alcohol while you are taking Terbinafine, because liber problem may
occur. Contack you doctor if you experience any discomforts, for example, nausea, vomiting, loss of appetite,
yellow eys or skin.
Finsh the medication even if you feel better.
Bramazil
Organisms Affected
Fungi