Ternbinafine HCl
Brand names,
Ternbinafine HCl
Analogs
Ternbinafine HCl
Brand Names Mixture
Ternbinafine HCl
Chemical_Formula
C21H25N
Ternbinafine HCl
RX_link
http://www.rxlist.com/cgi/generic/terbin.htm
Ternbinafine HCl
fda sheet
Ternbinafine HCl
msds (material safety sheet)
Ternbinafine HCl
Synthesis Reference
A. Stutz, Eur. pat. Appl. 24,587 (1981 to Sandoz)
Ternbinafine HCl
Molecular Weight
291.43 g/mol
Ternbinafine HCl
Melting Point
195-198 oC
Ternbinafine HCl
H2O Solubility
Slightly soluble
Ternbinafine HCl
State
Solid
Ternbinafine HCl
LogP
6.466
Ternbinafine HCl
Dosage Forms
Tablet; Cream; Spray
Ternbinafine HCl
Indication
For the treatment of interdigital tinea infections.
Ternbinafine HCl
Pharmacology
Terbinafine is an allylamine antifungal agent and acts by inhibiting squalene epoxidase, thus blocking the biosynthesis of ergosterol, an essential component of fungal cell membranes. in vitro, mammalian squalene epoxidase is only inhibited at higher (4000 fold) concentrations than is needed for inhibition of the dermatophyte enzyme. Depending on the concentration of the drug and the fungal species test in vitro, Terbinafine may be fungicidal. However, the clinical significance of in vitro data is unknown.
Ternbinafine HCl
Absorption
Readily absorbed from gastrointestinal tract.
Ternbinafine HCl
side effects and Toxicity
No information avaliable
Ternbinafine HCl
Patient Information
Patient Information:
Discuss with you doctor about the risks of this medication before taking it.
Do not dring alcohol while you are taking Terbinafine, because liber problem may
occur. Contack you doctor if you experience any discomforts, for example, nausea, vomiting, loss of appetite,
yellow eys or skin.
Finsh the medication even if you feel better.
Ternbinafine HCl
Organisms Affected
Fungi