Terbina
Brand names,
Terbina
Analogs
Terbina
Brand Names Mixture
Terbina
Chemical_Formula
C21H25N
Terbina
RX_link
http://www.rxlist.com/cgi/generic/terbin.htm
Terbina
fda sheet
Terbina
msds (material safety sheet)
Terbina
Synthesis Reference
A. Stutz, Eur. pat. Appl. 24,587 (1981 to Sandoz)
Terbina
Molecular Weight
291.43 g/mol
Terbina
Melting Point
195-198 oC
Terbina
H2O Solubility
Slightly soluble
Terbina
State
Solid
Terbina
LogP
6.466
Terbina
Dosage Forms
Tablet; Cream; Spray
Terbina
Indication
For the treatment of interdigital tinea infections.
Terbina
Pharmacology
Terbinafine is an allylamine antifungal agent and acts by inhibiting squalene epoxidase, thus blocking the biosynthesis of ergosterol, an essential component of fungal cell membranes. in vitro, mammalian squalene epoxidase is only inhibited at higher (4000 fold) concentrations than is needed for inhibition of the dermatophyte enzyme. Depending on the concentration of the drug and the fungal species test in vitro, Terbinafine may be fungicidal. However, the clinical significance of in vitro data is unknown.
Terbina
Absorption
Readily absorbed from gastrointestinal tract.
Terbina
side effects and Toxicity
No information avaliable
Terbina
Patient Information
Patient Information:
Discuss with you doctor about the risks of this medication before taking it.
Do not dring alcohol while you are taking Terbinafine, because liber problem may
occur. Contack you doctor if you experience any discomforts, for example, nausea, vomiting, loss of appetite,
yellow eys or skin.
Finsh the medication even if you feel better.
Terbina
Organisms Affected
Fungi