Terbinafine

Terbinafine Brand names, Terbinafine Analogs

Terbinafine Brand Names Mixture

No information avaliable

Terbinafine Chemical_Formula

C₂₁H₂₅N

Terbinafine RX_link

http://www.rxlist.com/cgi/generic/terbin.htm

Terbinafine fda sheet

Terbinafine FDA

Terbinafine msds (material safety sheet)

Terbinafine MSDS

Terbinafine Synthesis Reference

A. Stutz, Eur. pat. Appl. 24,587 (1981 to Sandoz)

Terbinafine Molecular Weight

291.43 g/mol

Terbinafine Melting Point

195-198 ^oC

Terbinafine H₂O Solubility

Slightly soluble

Terbinafine State

Solid

Terbinafine LogP

6.466

Terbinafine Dosage Forms

Tablet; Cream; Spray

Terbinafine Indication

For the treatment of interdigital tinea infections.

Terbinafine Pharmacology

Terbinafine is an allylamine antifungal agent and acts by inhibiting squalene epoxidase, thus blocking the biosynthesis of ergosterol, an essential component of fungal cell membranes. in vitro, mammalian squalene epoxidase is only inhibited at higher (4000 fold) concentrations than is needed for inhibition of the dermatophyte enzyme. Depending on the concentration of the drug and the fungal species test in vitro, Terbinafine may be fungicidal. However, the clinical significance of in vitro data is unknown.

Terbinafine Absorption

Readily absorbed from gastrointestinal tract.

Terbinafine side effects and Toxicity

No information avaliable

Terbinafine Patient Information

Patient Information:

Discuss with you doctor about the risks of this medication before taking it.
Do not dring alcohol while you are taking Terbinafine, because liber problem may
occur. Contack you doctor if you experience any discomforts, for example, nausea, vomiting, loss of appetite,
yellow eys or skin.
Finsh the medication even if you feel better.

Terbinafine Organisms Affected

Fungi