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TPS23 Brand names, TPS23 Analogs

TPS23 Brand Names Mixture

  • No information avaliable

TPS23 Chemical_Formula


TPS23 RX_link

TPS23 fda sheet

TPS23 msds (material safety sheet)

TPS23 Synthesis Reference

No information avaliable

TPS23 Molecular Weight

386.576 g/mol

TPS23 Melting Point

No information avaliable

TPS23 H2O Solubility

No information avaliable

TPS23 State


TPS23 LogP


TPS23 Dosage Forms

Tablet (10 mg, 25 mg, 50 mg, 100 mg) for oral administration; Ampuls (1 mL) for intramuscular administration; Concentrate for oral administration

TPS23 Indication

Used in the treatment of schizophrenia, organic brain disorders, alcoholism and psychoneuroses.

TPS23 Pharmacology

Mesoridazine, the besylate salt of a metabolite of thioridazine, is a phenothiazine tranquilizer. Pharmacological studies in laboratory animals have established that mesoridazine has a spectrum of pharmacodynamic actions typical of a major tranquilizer. In common with other tranquilizers it inhibits spontaneous motor activity in mice, prolongs thiopental and hexobarbital sleeping time in mice and produces spindles and block of arousal reaction in the EEG of rabbits. It is effective in blocking spinal reflexes in the cut and antagonizes d-amphetamine excitation and toxicity in grouped mice. It shows a moderate adrenergic blocking activity in vitro and in vivo and antagonizes 5-hydroxytryptamine in vivo. Intravenously administered, it lowers the blood pressure of anesthetized dogs. It has a weak antiacetylcholine effect in vitro.

TPS23 Absorption

Well absorbed from the gastrointestinal tract.

TPS23 side effects and Toxicity

Oral LD50 is 560 ± 62.5 mg/kg and 644 ± 48 mg/kg in mouse and rat, respectively. Symptoms of overdose may include emesis, muscle tremors, decreased food intake and death associated with aspiration of oral-gastric contents into the respiratory system.

TPS23 Patient Information

TPS23 Organisms Affected

Humans and other mammals