Serentil Concentrate
Serentil Concentrate Brand names, Serentil Concentrate Analogs
Serentil Concentrate Brand Names Mixture
- No information avaliable
Serentil Concentrate Chemical_Formula
C21H26N2OS2
Serentil Concentrate RX_link
http://www.rxlist.com/cgi/generic3/mesoridazine.htm
Serentil Concentrate fda sheet
Serentil Concentrate msds (material safety sheet)
Serentil Concentrate Synthesis Reference
No information avaliable
Serentil Concentrate Molecular Weight
386.576 g/mol
Serentil Concentrate Melting Point
No information avaliable
Serentil Concentrate H2O Solubility
No information avaliable
Serentil Concentrate State
Solid
Serentil Concentrate LogP
4.485
Serentil Concentrate Dosage Forms
Tablet (10 mg, 25 mg, 50 mg, 100 mg) for oral administration; Ampuls (1 mL) for intramuscular administration; Concentrate for oral administration
Serentil Concentrate Indication
Used in the treatment of schizophrenia, organic brain disorders, alcoholism and psychoneuroses.
Serentil Concentrate Pharmacology
Mesoridazine, the besylate salt of a metabolite of thioridazine, is a phenothiazine tranquilizer. Pharmacological studies in laboratory animals have established that mesoridazine has a spectrum of pharmacodynamic actions typical of a major tranquilizer. In common with other tranquilizers it inhibits spontaneous motor activity in mice, prolongs thiopental and hexobarbital sleeping time in mice and produces spindles and block of arousal reaction in the EEG of rabbits. It is effective in blocking spinal reflexes in the cut and antagonizes d-amphetamine excitation and toxicity in grouped mice. It shows a moderate adrenergic blocking activity in vitro and in vivo and antagonizes 5-hydroxytryptamine in vivo. Intravenously administered, it lowers the blood pressure of anesthetized dogs. It has a weak antiacetylcholine effect in vitro.
Serentil Concentrate Absorption
Well absorbed from the gastrointestinal tract.
Serentil Concentrate side effects and Toxicity
Oral LD50 is 560 ± 62.5 mg/kg and 644 ± 48 mg/kg in mouse and rat, respectively. Symptoms of overdose may include emesis, muscle tremors, decreased food intake and death associated with aspiration of oral-gastric contents into the respiratory system.
Serentil Concentrate Patient Information
Serentil Concentrate Organisms Affected
Humans and other mammals
