Streptozocin en es it fr

Streptozocin Brand names, Streptozocin Analogs

Streptozocin Brand Names Mixture

  • No information avaliable

Streptozocin Chemical_Formula


Streptozocin RX_link

Streptozocin fda sheet

Streptozocin msds (material safety sheet)

Streptozocin Synthesis Reference

No information avaliable

Streptozocin Molecular Weight

265.221 g/mol

Streptozocin Melting Point

115 oC

Streptozocin H2O Solubility

5070 mg/L

Streptozocin State


Streptozocin LogP


Streptozocin Dosage Forms

Powder for solution

Streptozocin Indication

For the treatment of malignant neoplasms of pancreas (metastatic islet cell carcinoma).

Streptozocin Pharmacology

Streptozocin is an antitumour antibiotic consisting of a nitrosourea moiety interposed between a methyl group and a glucosamine. Streptozocin is indicated in the treatment of metastatic islet cell carcinoma of the pancreas. Streptozocin inhibits DNA synthesis in bacterial and mammalian cells. In bacterial cells, a specific interaction with cytosine moieties leads to degradation of DNA. The biochemical mechanism leading to mammalian cell death has not been definitely established; streptozocin inhibits cell proliferation at a considerably lower level than that needed to inhibit precursor incorporation into DNA or to inhibit several of the enzymes involved in DNA synthesis. Although streptozocin inhibits the progression of cells into mitosis, no specific phase of the cell cycle is particularly sensitive to its lethal effects.

Streptozocin Absorption

Poor oral absorption (17-25%)

Streptozocin side effects and Toxicity

Symptoms of overdose include nausea and vomiting, anorexia, myelosuppression; and nephrotoxicity.

Streptozocin Patient Information

No information avaliable

Streptozocin Organisms Affected

Humans and other mammals