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Zanosar Brand names, Zanosar Analogs

Zanosar Brand Names Mixture

  • No information avaliable

Zanosar Chemical_Formula


Zanosar RX_link

Zanosar fda sheet

Zanosar msds (material safety sheet)

Zanosar Synthesis Reference

No information avaliable

Zanosar Molecular Weight

265.221 g/mol

Zanosar Melting Point

115 oC

Zanosar H2O Solubility

5070 mg/L

Zanosar State


Zanosar LogP


Zanosar Dosage Forms

Powder for solution

Zanosar Indication

For the treatment of malignant neoplasms of pancreas (metastatic islet cell carcinoma).

Zanosar Pharmacology

Streptozocin is an antitumour antibiotic consisting of a nitrosourea moiety interposed between a methyl group and a glucosamine. Streptozocin is indicated in the treatment of metastatic islet cell carcinoma of the pancreas. Streptozocin inhibits DNA synthesis in bacterial and mammalian cells. In bacterial cells, a specific interaction with cytosine moieties leads to degradation of DNA. The biochemical mechanism leading to mammalian cell death has not been definitely established; streptozocin inhibits cell proliferation at a considerably lower level than that needed to inhibit precursor incorporation into DNA or to inhibit several of the enzymes involved in DNA synthesis. Although streptozocin inhibits the progression of cells into mitosis, no specific phase of the cell cycle is particularly sensitive to its lethal effects.

Zanosar Absorption

Poor oral absorption (17-25%)

Zanosar side effects and Toxicity

Symptoms of overdose include nausea and vomiting, anorexia, myelosuppression; and nephrotoxicity.

Zanosar Patient Information

No information avaliable

Zanosar Organisms Affected

Humans and other mammals