Retrocortine

Retrocortine Brand names, Retrocortine Analogs

Retrocortine Brand Names Mixture

Cortab (Biotin + Chlorpheniramine Maleate + D-Pantothenic Acid + Inositol + Nicotinic Acid + Prednisone + Pyridoxine Hydrochloride + Thiamine Mononitrate + Vitamin a + Vitamin B2 + Vitamin D + Vitamin E (Dl-Alpha Tocopheryl Acetate))
Metreton Tab (Chlorpheniramine Maleate + Prednisone + Vitamin C)
Predniderm Tab (Inositol + Pheniramine Maleate + Phosphatidyl Choline + Prednisone + Vitamin a + Vitamin D2 + Vitamin E)
Sterolin Liq (Biotin + Fatty Acids Unsaturated + Inositol + Nicotinic Acid + Pheniramine Maleate + Phosphatidyl Choline + Prednisone + Vitamin a Palmitate + Vitamin B2 + Vitamin D2 + Vitamin E)

Retrocortine Chemical_Formula

C₂₁H₂₆O₅

Retrocortine RX_link

http://www.rxlist.com/cgi/generic/pred.htm

Retrocortine fda sheet

Retrocortine msds (material safety sheet)

Retrocortine MSDS

Retrocortine Synthesis Reference

Oliveto, Gould, U.S. Pat. 2,897,216 (1959)

Retrocortine Molecular Weight

358.428 g/mol

Retrocortine Melting Point

233 - 235 ^oC

Retrocortine H₂O Solubility

312 mg/L

Retrocortine State

Solid

Retrocortine LogP

1.471

Retrocortine Dosage Forms

Tablets; Ointments; Cream; Oral Solution

Retrocortine Indication

Systemic use: for the treatment of drug-induced allergic reactions, perennial or seasonal allergic rhinitis, serum sickness, giant cell arteritis acute rheumatic or nonrheumatic carditis, systemic dermatomyositis, systemic lupus erythematosus, atopic dermatitis, contact dermatitis, exfoliative dermatitis, bullous dermatitis herpetiformis, severe seborrheic dermatitis, severe (Stevens-Johnson syndrome) erythema multiforme, mycosis fungoides, pemphigus, severe psoriasis, acute adrenocortical insufficiency, Addison's disease, secondary adrenocortical insufficiency, congenital adrenal hyperplasia, hypercalcemia associated with neoplasms, nonsuppurative thyroiditis, ulceratice colitis, Crohn's disease, acquired hemolytic anemia, congenital hypoplastic anemia, erythroblastopenia, adult secondary thrombocytopenia, adult idiopathic thrombocytopenia purpura, acute or subacute bursitis, epicondylitis, acute nonspecific tenosynovitis, acute or chronic lymphocytic leukemia, Hodgkin's or non-Hodgkin's lynphomas, Waldenstrom's macroglobulinemia, primary brain tumors (adjunct), nephrotic syndrome, tuberculous meningitis, multiple sclerosis, myasthenia gravis. cerebral edema, chorioretinitis, diffuse posterior choroiditis, aleergic conjunctivitis, Herpes zoster ophthalmicus, anterior segment inflammation, iridocyclitis, iritis, keratitis, optoc neuritis, sympathetic ophthalmia, corneal marginal allergic ulcers, symptomatic sarcoidosis, Loeffler's syndrome not manageable by other means, berylliosis, fulminating or disseminated pulmonary tuberculosis when used concurrently with appropriate antituberculous chemotherapy and aspiration pneumonitis.

Retrocortine Pharmacology

Prednisone, the most commonly-prescribed corticosteroid, is used to treat allograft rejection, asthma, systemic lupus erythematosus, and many other inflammatory states. Prednisone has very little mineralocorticoid activity.

Retrocortine Absorption

Readily absorbed from the gastrointestinal tract.

Retrocortine side effects and Toxicity

LD₅₀=mg/kg (orally in rat)

Retrocortine Patient Information

Persons who are on immunosuppressant doses of corticosteroids should be warned to avoid exposure to chicken pox or measles. Patients should also be advised if they are exposed, medical advice should be sought without delay.

Retrocortine Organisms Affected

Humans and other mammals