Retavase (Roche)
Retavase (Roche) Brand names, Retavase (Roche) Analogs
Retavase (Roche) Brand Names Mixture
- No information avaliable
Retavase (Roche) Chemical_Formula
C1736H2671N499O522S22
Retavase (Roche) RX_link
http://www.rxlist.com/cgi/generic2/reteplase.htm
Retavase (Roche) fda sheet
Retavase (Roche) msds (material safety sheet)
Retavase (Roche) Synthesis Reference
No information avaliable
Retavase (Roche) Molecular Weight
39589.6
Retavase (Roche) Melting Point
60 oC (Novokhatny, V.V. et al., J. Biol. Chem. 266:12994-123002 (1991))
Retavase (Roche) H2O Solubility
No information avaliable
Retavase (Roche) State
Liquid
Retavase (Roche) LogP
-0.435
Retavase (Roche) Dosage Forms
Solution (IV injection); Powder for solution
Retavase (Roche) Indication
For lysis of acute pulmonary emboli, intracoronary emboli and management of myocardial infarction
Retavase (Roche) Pharmacology
Retavase cleaves the Arg/Val bond in plasminogen to form plasmin. Plasmin in turn degrades the fibrin matrix of the thrombus, thereby exerting its thrombolytic action. This helps eliminate blood clots or arterial blockages that cause myocardial infarction.
Retavase (Roche) Absorption
No information avaliable
Retavase (Roche) side effects and Toxicity
No information avaliable
Retavase (Roche) Patient Information
No information avaliable
Retavase (Roche) Organisms Affected
Humans and other mammals
