Quinacrine Dihydrochloride
Quinacrine Dihydrochloride Brand names, Quinacrine Dihydrochloride Analogs
Quinacrine Dihydrochloride Brand Names Mixture
- No information avaliable
Quinacrine Dihydrochloride Chemical_Formula
C23H30ClN3O
Quinacrine Dihydrochloride RX_link
No information avaliable
Quinacrine Dihydrochloride fda sheet
Quinacrine Dihydrochloride msds (material safety sheet)
Quinacrine Dihydrochloride Synthesis Reference
No information avaliable
Quinacrine Dihydrochloride Molecular Weight
399.957 g/mol
Quinacrine Dihydrochloride Melting Point
248-250 oC
Quinacrine Dihydrochloride H2O Solubility
Slight
Quinacrine Dihydrochloride State
Solid
Quinacrine Dihydrochloride LogP
5.388
Quinacrine Dihydrochloride Dosage Forms
Tablet
Quinacrine Dihydrochloride Indication
For the treatment of giardiasis and cutaneous leishmaniasis and the management of malignant effusions.
Quinacrine Dihydrochloride Pharmacology
Quinacrine has been used as an antimalarial drug and as an antibiotic. It is used to treat giardiasis, a protozoal infection of the intestinal tract, and certain types of lupus erythematosus, an inflammatory disease that affects the joints, tendons, and other connective tissues and organs. Quinacrine may be injected into the space surrounding the lungs to prevent reoccurrence of pneumothorax. The exact way in which quinacrine works is unknown. It appears to interfere with the parasite's metabolism.
Quinacrine Dihydrochloride Absorption
Absorbed rapidly from the gastrointestinal tract following oral administration.
Quinacrine Dihydrochloride side effects and Toxicity
Oral, rat: LD50 = 900 mg/kg; Oral, mouse: LD50 = 1000 mg/kg. Symptoms of overdose include seizures, hypotension, cardiac arrhythmias, and cardiovascular collapse.
Quinacrine Dihydrochloride Patient Information
This medication is best taken after meals with a full glass of water,
fruit juice, or tea, unless your doctor instructs otherwise. Tablets may be crushed and mixed with chocolate syrup,
honey, or jam for persons who cannot stand the bitter taste or have difficulty swallowing tablets. If you miss a
dose, take it as soon as you remember. If it is near the time for the next dose, skip the missed dose and resume your
regular dosage schedule. Do not double the next dose. Take it as prescribed for the full treatment period, even if
you feel better before the scheduled end of therapy.
Quinacrine Dihydrochloride Organisms Affected
Parasitic protozoa and helminths
